Could our issues be dopamine related?

Please keep us updated. If it works well I may try. If I may ask how long have you had pfs?

Hey I have PSSD. Same shit just different drug that kicked off this nightmare. I have had this full syndrome for 7 months now but looking back was suffering from “mild” PSSD for a couple years but didn’t know it. Stupidly took antidepressants again and made it worse. Anyway I started the Cabergoline last week to lower my Prolactin which is high. Haven’t noticed much yet. The Addyi I started 2 nights ago. That will take a few months to work. I got a decent sleep last night taking it with my Halcion and Lyrica. Took a small dose of Adderall today. Hard to tell cause I have NO emotions but I noticed I have some decent energy today. The DHEA is making me break out a little but that’s ok cause I need some oil to help this dry skin. I will keep you updated and try to write a more detailed review of my Goldstein visit. My memory is so shot right now.

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Take your time and be easy with with yourself. Appreciate the update.

Mcbbould,

Im not singling you out buddy but a lot of people here act like our receptors are like flowers and grow and prosper like flowers. I hear wild things like “heal your receptors”… This is not the case. Nuclear steroid receptors are just intertangled proteins that get put together by the cells in our body. They get degraded then reform. They aren’t like wilting or anything like that from lack of signaling. Hope this makes snede

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So that’s good news lol?

depends if we find out what has caused this dysregulation

i think so too but how can our problem be dopamine related, is dopamine related in AR activity? maybe something like l dopa (mucuna dopa as a supplement) could help us.

This is my first day/ post since ceasing Finasteride back on 4/Jan/2019. I was on the poison for 22 years. I had most of those symptoms in my first crash cycle. I am currently enduring my second crash cycle which but am relieved to report it has been mostly free of muscle twitches, light headedness and hypnopompy - that’s some improvement which keeps the dim light of hope burning.

While i had some symptoms on the drug; low energy, abnormal mood fluctuation, muscle aches and mild ED things are 100 times worse since ceasing. My burning question is should i reinstate the drug as I could at least function while i was on it. Anyone thought the same or tried it?

No, it’s high-risk going by other cases of people attempting the same thing. You are likely to become irreversibly worse off.

Thanks so much for your reply - it echoes my thoughts. Its so confusing what the best move is. What is certain is I cant continue in my current state. I’m trying Saw Palmetto - cant say its given any notable improvement though.

Ive felt for sometime that my Dopamine regulation is off, particularly as i experience akathisia. I am interested in trying a Dopamine agonist though living in Australia means i have very limited options in terms of Doctors who have a clue about this. I wasted $500 on Greg Emerson (the guy hasn’t a clue about PFS and is shamelessly profiting in my view).

I look forward to hearing about the Dopamine agonist results however.

Hey @poisoned are you aware that Saw Palmetto is what caused PFS for some members on here? It’s a 5-AR inhibitor. Search stories about it causing members PFS on here. I would consider it extremely high risk, and I think most members on here would warn you against it.

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Hi, thanks for taking the time to reply.
Yes I’m aware of its 5-AR inhibition/ mitigation particularly in relation DHT serum levels in the prostate and urinary tract - the reason for me taking it. However, I will give it more consideration in light of your comment - thanks. Though it does seem to improve some of my prostate related symptoms.

Stay away from saw palmetto you should not be taking that poison

OK…thank you! have you experienced issues with it?

I crashed using a shampoo that contained both ketokonzale and saw palmetto it’s been around a year now and I’m severely messed up without any improvements, getting worse in fact.

https://m.youtube.com/watch?v=4z5s3UEjzlQ He took this shit and took his life do not use it

Wow, OK point taken I’ll stop. I really appreciate the warning and on reflection my current crash coincides with with its initiation. Strange though as when i first started it my ED and ejaculatory response improved. My thoughts were that due to epigenetic changes my system was struggling with the higher level of DHT and therefore some reduction may be of benefit.

Yeah man I know most people think saw palmetto is safe because its natural but it’s definitely not I just wish I could go back and live a normal life again

I hear you brother!
It seems i mucked up on this one…just threw them in the bin. You get so desperate for improvement that sometimes you act in haste. I’m so grateful for the heads up from you guys. I’m sure we’ll get through this.
Have you tried French Maritime bark extract to increase Nitric Oxide levels??

Never heard of it I’ll look into it though.

I found it to improve erections on the back of some very good double blind clinical cross over trials. I recommended it to another PFS sufferer who found in improved things too.