blood test - way

Hi everybody, here my exams, sorry but they are expressed in italian values (but with the range values it’s easy to see if they are good):

Testosterone: 2,84 ng/ml ----------> range (2,41 - 8,27)
LH: 3,37 mU.I./ml ----------------> range (2,0 - 12 )
FSH: 3,43 mU.I./ml ----------------> range (1,7 - 12)
Cortisol: 243,8 ng/ml ---------------> range (50 - 250)
E2: 65,12 pg/ml ---------------> in a men must be <62
ACTH 70,60 --------------------------> in a men must be <46
(why acth isn’t in the importat exam to do?
http://www.vivo.colostate.edu/hbooks/pathphys/endocrine/hypopit/acth.html )

psa and TSH was ok in a exam of 2 month ago so i did’t repeat them.

what do you think about my exams? i’m happy because my E2 and cortisol are very high (and testosterone is low), so it can be a possible cause…!?
please give me your opinion

If these tests were performed in the morning, you look to suffer from hypogonadism. Your E2 is too high, and by bringing that down, might increase your testosterone.

Your cortisol looks fine, the range is flawed, and young men are supposed to be at the top of reference, if not over.

Your acth shows your body are “asking” for more cortisol, maybe taking these tests stressed you?

Maybe taking some Arimedex or DIM will help you, but Im sure hypo will give his opinion too.

JH

Clear Hypogonadism if you go off of total/serum testosterone as Legenden has said as long as these are morning tests.

Your total testosterone level if converted to European and US reference ranges equates to 9.85nmol/l or 284ng/dl.

This would be recognized as subnormal and hypogonadal in the UK and the US and appears also to be recognized as such by your laboratories reference range.

All the above said total/serum testosterone alone is not the best indicator of androgen status and the likelihood of hypogonadism. Yes you certainly look as though you have hypogonadism, but to evaluate your androgen status more fully and get an idea of the severity of such problems……

You should take the hypogonadal checklist on the main forum and see how you do on that. The severity of hypogonadism is usually very well reflected in your symptomatic score via that subjective test.

A further a better analysis of your androgen status to gauge the severity of problems would also be to have your free testosterone tested.

If you cannot obtain a free testosterone test in your country or at least it is very difficult then you can obtain a guestimate of your free testosterone by having an SHBG test.

If you give me your SHBG test I will calculate your free testosterone and this is something you can pass on to your endocrinologist and is something that he will acknowledge.

SHBG should be tested for anyway because it is also a factor relating to estrogen status and the extent to which estradiol maybe causing problems and potentially lowering both total and free testosterone.

I say that because your estradiol level is also too high, even without considering SHBG because it is in the upper third of the male reference range and this is a level which is more common in older men and a level that can cause problems by acting against the actions of testosterone in the male.

Finally finasteride’s principle mechanism of action is to block/lower the potent androgen dihydrotestosterone (DHT), for this reason and because low DHT independently causes problems, you need this tested as well.

So to sum up then;

A)
Take the hypogonadal checklist and see how you do and post your result in this thread.

B)
Have a free testosterone, SHBG and DHT test- post the results in this thread.

C)
You appear hypogonadal based on total testosterone at this moment.

D)
Whether this is a permanent situation or not depends on the time since you have last taken endocrine altering meds like finasteride and is something that needs to be considered further with a medical professional.

E)
It is better to have your situation investigated fully before any medication is considered or prescribed.

Consider the views of others not just myself.

If you wish to pass on anything I posts to you; you are welcome to show it to any endocrinologist or doctor because I am confident in its validity.

P.S

I wont comment on the results outside of those relating to sex hormones as I understand them less well and will leave that for others.

I hope that helps a bit. It is pretty much just adding to what has already been covered.

thank you hypo for your opinion! i’ll try to do shgb, dht and free T exams…
hypogonadal checklist score: 21 = likely

a worryng aspect of my sides is that my four principal side: ED, loss libido, state of fatigue, raise of abdominal fat are getting every month worste
(i stop fina in 2003 [i took it for six month] and since 2003 i’m getting progressively worste…)
is that a symptom of something?
is that a clue for something?
(for example hypogonadism?)

thanks everybody!

I thought you would have a higher/worse symptomatic score.

Given that I think your SHBG might be low, or at least your free testosterone be indicative of a less serious problem than your total testosterone sugests.

That said you do obviously have a hormonal problem- just not as bad as it could be.

Your symptoms could be down to a relatively low free testosterone level, or a low DHT level- or even simply by the elevated estradiol level.

Once you have the further tests you will hopefully have a better idea of the nature of the problem, at least if your issues are of a hypogonadal nature as it appears

ok, thank you very much , i’ll post my next results (if i am able to abtain it!) :wink:

today i’ve been to my endo for show him my blood test.
he says: “your testo and your estradiol level indicate that there are no hormonal problems! so don’t worry”
i’m very frustated… very very frustated… (my E2 is out of range, how can i have no hormonal problem??)

however my cortisol and my acth was high and so he decided to give me 1 mg of decadron (DEXAMETHASONE) and repeat my cortisol and acth tests in order to make a test to see if i have hypercorticism.
what do you think about that? somebody here have hypercorticism?

(loss of libido and Ed are side of hypercorticism… )

He is categorically wrong regarding the testosterone and estradiol levels.

What you do about that is upto you.

I can’t comment too much on the cortisol issue and will leave that for someone else.

Out of interest what country are you in?

i am from italy…
why endo are so superficial??

update:

my free t is: 5,9 pg/ml (5,6 - 40)

A relatively low free testosterone level as I suggested given your symptoms and bloods.

That level does not represent hypogonadism according if an endocrinologists goes off of overly strict reference range definitions but it would certainly be regarded as hypogonadism given the symptoms and levels in the US, as such it would be treated.

Even when looking at the reference range, if you were to go off of the 5th percentile of normal for your age (if your are under 40) then I am sure it would be categorically too low and regarded as hypogonadal.

Your free testosterone level is more typical of a man in their 60s/70s.

thank you hypo, you’re are always very kind. i’m 22 years old…
the endo will not treat me. so i must go to another endo, spend other money…and hope somebody stop say me that i have only psychological problem (the most frequent answer of the endo/urologist) :frowning:

Go back to your endocrinologist and show him this…when you do take out the brackets comment that I am making to you :wink:

The information/links below are from Schering pharmaceutical company. These are the people behind the manufacture of many testosterone replacement products and are experts in the field of the endocrinology of this condition.

Ask your doctor to view this page from and in particular their hypogonadism checklist.

He should note that symptoms; 5, 6, 7, 8 and 11 can easily be mistaken for psychological problems when they can in fcat be part of a hormonal imbalance.

get-back-on-track.com/en/con … _03_02.php

Looking at your total testosterone alone.

Your result of 2.84ng/ml equals 9.85nmol/l on the European range.

As can be seen when converted using the interactive testosterone calculator- 7th box down on the right

get-back-on-track.com/en/pro … _01_03.php

With the above in mind he should view this page

get-back-on-track.com/en/pro … _01_05.php

And the first box on the left.

Look at where that puts you for age for total testosterone.

Furthermore hew should view what Schering regard as an acceptable testosterone level 5th box down on the right hand side (I do not agree with their range as it happens but that is not the point you can use this to show your endocrinologist :slight_smile:

get-back-on-track.com/en/pro … _01_03.php

I hope this helps

Here are my last exams:

FT4: 1,11 ng/dl --------------------- (0,70 - 1,70)
TSH: 1,89 mcUl/ml ------------------(0,25 - 5,00)
Cortisolo: 260 ng/ml -----------------(50 - 250)
ACTH: 50,1 pg/ml -------------------(< 46)
Testosterone: 4,03 ng/ml--------------(2,41 - 8,27)
Estradiol: 248,43 pg/ml ----------------(in a men must be < 62)

what do you think about it?

Your Estradiol is insanely high, start taking DIM or try low dose Arimidex to bring it down. Might want to investigate Adrenal Fatigue as well, due to a high ACTH and Cortisol.

Have u done a typo on yr estradiol number? 248 on a scale less than 62 sounds really really high. also yr last labs came back with high e2 but no way near as high as this. Has yr doctor seen this result or did u just contact a lab on yr own and got the results directly to u? if he has seen them he must have had something to say in regards to yr clearly elevated e2 results.

How do u feel ? I would say u getting progressibly worse is connected to yr ongoing elevation of estradiol. Tummy fat connected to this also. I cant beleive yr doctor dont start an investigation as to understand what is going on, if he wont act on this i think u should look elsewhere for a doctor that takes yr problems with the attitude they require. Mews proposal about dim and arimidex sounds like a good starting point.

I have spoken to way on msn, we live quite near to eaxh other hear in Italy and were giving each other a hand. I reccomended to get the same gnrh stimulation test I had because this could be a case of Hypogonadism. We are trying to find a good endo near us but it’s not so easy…
Personal view on the results: maybe his testosterone is trying to get back to normal(from 2,84 to 4,00) and it’s still excessively aromatizing.
A gnrh stimulation test to see if lh and fsh are responding well would clearify the situation further

yes 248 it very high… and in fact, my actual situation is that i haven’t any sexual stimuation, e feel like a dead, i’m total unable to keep a decent erection, my abdominal fat is at the maximum size of even. the doctor that has seen my previous exams was an endo that has said that they was “normal”… so i’m searching for a new endo in order to show him this last (worst) exams…

i toke broccoli juice in the past with great result in the first days; now i’m waiting for DIM supplements…

You need a full and proper forward thinking endocrine investigation from someone well versed in male hormonal issues.

When you have that you need to fully detial your medical history and use of finasteride and the problems found on finasteride worldwide/let them view the website and give them the contact details for Dr Crilser and/or Dr Shippen.

Stop messing around with broccoli and forget DIM.

You need proper professional help here and correct treatment.

UPDATE:
hi, after 3 month on TRT + nolvadex (tamoxifene) 10 mg per day i had this blood test:

E2: 68 pg/mL ------------------------------------------Range:(12 - 41)
Testosterone: 17,89 ng/mL --------------------------------(2.80 - 8)
Free Testosterone: 50.66 pg/mL -------------------------(8.69 - 54.69)
PSA: 1,57 ng/mL -----------------------------------------------(0 - 4)

ps: this blood test was done 3 day after the puncture of testosterone, and now i’m waiting for the blood test of the 27th day after the puncture.

ps2: i don’t fell any tipe of improvement…

ps3: the previous exams with a e2 level of 248 was probably uncorrect, because i have do it again (2 times) and e2 was in the normal range…