Straight from Khera about 30 mins ago…
“Already accepted for publication. I expect the EPUB version to be out in the next couple weeks”.
Mohit Khera, MD
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Do you know if the plan is still for a two part release?
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The abstract of one study from them is already available online
Hopefully, Khera is saying the genome expression analysis is to publish soon
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Thanks man. Interesting stuff.
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This appears to be a summary of Khera’s presentation from the SMSNA conference last year. It’s published in a supplement to a Journal of Sexual Medicine issue.
We’ll have to wait to see what they end up publishing. I don’t think this is part one of their study because it doesn’t appear to be peer-reviewed and its not even a full page. You can see the conclusion by looking at the next section (#125).
Yes, I think I may have used too strong a word in “published”. The abstract of that publication has been available online since September 2019
Axolotl gave some clarity over the “two part” confusion here
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sorry, im super tired right now and confused
so neither part 1 or 2 are published, but we hope that the full thing gets published in the next few weeks?
thanks a lot
Donde se encuentra? Gracias.
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Is this the Baylor Study? https://www.pfsfoundation.org/news/penile-vascular-abnormalities-found-in-majority-of-pfs-patients-in-baylor-college-of-medicine-study/
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Looks like to me…
That is study 1. Study 2 deals with epigenetics and has an unknown publish date.
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Yeah, but this is published now, and for the epigenetics study will have to wait 10 years more 
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Its ridiculous it took that long for that bullshit of a study to be posted makes 0 sense
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“Since two of the PFS patients (8%) committed suicide during or after the research period, Khera suggests that “psychiatric side effects and the risks of finasteride use in patients with a history of psychiatric disorders should be investigated further…” Who said they had a history of psychiatric disorders? They did?
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I agree this quite upsetting. Seems like he’s pointing at underlying mental illness when its not required at all for this to end someone. I guess it doesn’t help but it just sounds like things drugs companies use to justify themselves. It causes mental illness, not just amplifies whats already there.
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OK, I am wondering why after the release of the Baylor study there is such a silence here on this website? I mean, so many years of anticipation and then all of a sudden silence, like nothing happened. 
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@tisho1012 I spoke about this in another thread.
This study Baylor study, part 1 - Penile vascular abnormalities in young men with persistent side effects after finasteride use for the treatment of androgenic alopecia. 2020 is a publication from Baylor. When the foundation announced a “major clinical study” with Baylor, these were the areas of investigation outlined
Methods: To (i) evaluate sexual and psychological function, (ii) assess hormone levels, (iii) measure penile hemodynamic and sensory parameters, (iv) study androgen receptor genetics and gene expression, and (v) and determine gene expression patterns and profiles.
Obviously not all of that is covered in the recent publication so hopefully there is more to come. I am not a spokesperson for the foundation or Baylor college of medicine. This is just my deduction, based on what information is already available.
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He’s not saying that these patients don’t have PFS, they had underlying psychiatric illnesses prior to taking PFS. He’s really just presented the facts and data because they could be useful. If we find out that having a pre-existing psychiatric illness increases the risk of getting PFS by 10-fold, that’s very useful information. Not just to people who are considering taking the drug, but also to us because it might suggest places to look where things may have gone wrong.
It does sound similar to PFS deniers and legal arguments that Merck would have tried to make in the litigation, but they’re actually quite different. From a purely scientific perspective it may add valuable information. These types of findings can be twisted and distorted and misinterpreted, but he’s not looking to discredit PFS at all.
Maybe having depression is the factor that makes you vulnerable to finasteride, but finasteride is the actual cause for making the situation 10x worse. But maybe there is no connection at all.
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