Epigenetics and Psychiatric Disease
https://www.sciencedirect.com/topics/neuroscience/trichostatin-a
3.3.3 Role of HDAC Inhibitors in TBI Pathology
HDAC inhibitors such as sodium butyrate (SB), valproic acid, trichostatin A, suberoylanilide hydroxamic acid, and so on have long been studied for their role in normalizing the deleterious consequences of environmental factors including addictive drugs and stress.101 Similarly, recent studies also show the neuroprotective effects of HDAC inhibitors via restoration of histone acetylation in the frontal cortex and hippocampus of TBI-induced animals.
Sodium butyrate : Sodium butyrate, the sodium salt of butyric acid, is a well-known HDAC inhibitor, and competitively binds to the zinc sites in class I and II HDACs. The administration of SB on the 14th day after CCI injury increases global histone acetylation in the hippocampus. In addition, SB also improves CCI-induced deficits in spatial learning and memory, as well as fear conditioning due to TBI.54
And there are a lot more information in this page