Some good concepts here when it comes to possible treatment.
Fate, activity, and impact of ingested bacteria within the human gut microbiota
Most of the data discussed above derive from studies on fecal material, which is believed to be representative of the colonic microbial populations. Much less is known about the microbiome of the small intestine, due mainly to the fact that it is accessible only with invasive sampling. The small intestine is the primary site of food digestion, nutrient absorption, and metabolic signaling.
Ingested bacteria can cause major shifts in the composition of the microbiome of the small intestine, whereas alterations in the colon are mostly of limited extent.
It is noteworthy to mention, in the context of this review, that these communities are highly specialized in the utilization of simple dietary carbohydrates, much like food-fermenting bacteria (see below) – which may therefore compete for the same niche in the small intestine. Microbial population densities in the small intestine are much lower than in the colon, ranging from 104 cells per gram in the duodenum to 108 cells per gram in the terminal ileum. Hence, the consumption of a dose of 1010 (10 billion) ingested bacterial cells is predicted to induce a dramatic population shift that temporarily overcrowds resident communities and which is likely to impact the host’s immune and neuroendocrine functions