About to start Daily Tadalafil (Cialis). Really Nervous! Any long term success?

Hey guys,

As many of you know, ED is my last remaining major PFS side effect thats remaining. While i am glad other sides have cleared, ED has remained and it has remained very strongly.

I can literally feel in my brain that the receptors and signals are not firing properly to induce an erection. I barely get morning wood and when i do they are 50% hard. There is a SIGNIFICANT lack of blood flow to my penis.

This is why i have turned to daily Tadalafil. I will start with 2.5mg/every day to stay on the safe side. My question is

  • What am i to expect? What should i be looking out for in the first weeks? What should i watch out for?

  • I am worried about being dependant on the drug or causing crash if i quit it. Has anyone had long term success with Cialis specifically for their PFS ED?

  • Do you think neuroligically, over time, it is possible for Cialis to “correct” the signals and receptors in my brain responsible for inducing an erection? In other words, Can Cialis resolve the ED issue at the neurological root not just “force” erections by blood flow? Can it help speed up overall ED recovery so that you can quit lets say after 3 months?

  • Can i mix viagra and cialis in low doses?

I know theres many here who are on cialis/have tried it! looking for your input,
Thank you in advance

  • I used 5mg daily for two years.
  • It did not give long run improvement. But I hope it stops (or at least slows) worsening as long as I take it.
  • Several urologists said risks are low and you don’t get insensitive to it (it remains equally effective) and also not dependant.
  • Biggest official risks that worry me are with respect to eyes and ears (there might be a very, very small risk of suddenly going blind/dead).
  • It does nog do anything neurological; just improve blood flow.
  • I recently stopped. I suddenly started getting stomach issues everytime I take it. Not sure how to continue.
  • I don’t think mixing is dangerous (as long as total dose is not too high).
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No, and no. Cialis is not going to cure your epigenetic Androgen Receptor Gene damage. Man, wake up before it is too late. I did the same mistake here 4 years ago.

I take cialis 20mg like a candy. And its just that, a small candy which can ‘‘help’’ a little to my bloodflow.

You need to up your game with some serious treatment options. Try androgens and hormonal theraphy.

I always get frustratingly confused when people mention this…

How much Fin does it take to have a long term ACTUAL damage on this?

I only took 3mg of Fin and then quit. Its been a zig zag recovery but 3 months in, I feel like i am making linear progress. If you look at my recent threads you will see that I currently have literally no symptoms EXCEPT ED.

Overall Sexual sides have improved and mind-penis connection as well in the recent days thank God.

Do i have a chance at full recovery?

Thanks for the insight

Although i am not currently sexually active, i will start tadalafil for overall penile health.

For what it’s worth, a 2019 meta-analysis found that Cialis use was not associated with NAION (non-arteritic anterior ischemic optic neuropathy [a form of vision loss]).
https://onlinelibrary.wiley.com/doi/10.1111/aos.14253

However, to my knowledge, there havent been any similiar papers about hearing loss caused by Cialis (or other ED pills).

That’s interesting - I wasn’t aware of the vision risk there.

Personally I’ve found tadalafil modestly helpful. It is by no means a radical improvement. There is no change in libido level - it just improves bloodflow somewhat.

The vision risk would be enough to put me off taking it every day.

Cialis does nothing either standalone or combined with tadalafi, for me. Cialis does seem to have some undesirable side effects - vision changes, feeling of blood pressure increase… after trialling it out, I don’t take it.

Thanks @BibFortuna , that is somewhat reassuring!

About hearing loss I didn’t look at papers. It is mentioned in my general information leaflet and on https://en.wikipedia.org/wiki/Tadalafil. I am unsure how to judge this. Of course if millions of people take a drug some will report incidents that are not related. But (after finasteride) I also tend to think pharmaceutical information deliberately downplays risks.

~5mg helps in the erection department and lasts for good 30+ hrs but somehow it made me depressed. I assumed it does this through its anti-estrogen effects. I come from a low E2 background so this may not be a concern.

I don’t want to be a downer. But man, are you sure?

Because it is very unlikely. It may be a gradual decline on other areas so you may not even noticed it? As an obsessive person, even i didn’t realize my own changes. This trauma from the disease masks some issues i would say. So, think twice. You have to face with the harsh reality as soon as you can to fix it.

If you have ED, you should also have sensivity loss, muscle and nerve weaknesses, probably prostate issues and related things.

But, you are very lucky if you are really sure that everything is 100% normal except for your Bloodflow to penis. :slight_smile: That’s nice bro.

That would indicate a physical problem, maybe get a full MRI on your nerves.

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