Any word yet from the researchers? And anyway to track down a researcher for Merck who designed finasteride in the 1990s? These guys will know the drug very well, and may be retired enough to help us. How could we find the name of a scientist who worked on this for Merck?
what an excellent idea. I donāt know, how can we find who monitorized the clinical trials?
No words from that researcherā¦I will email another one
I got this Poly MTHFR shit. I am doing a 23&meā¦ Not sure if that can be used to find more methylation problems or not.
Oh and I have high DHEAs last 3 testsā¦ And low cortisol.
I am taking T shots, Cortisol, and now l-methylfolate for the MTHFR shit. Feeling a bit better but still feel mentally altered in a bad way.
this mofoā¦heās 85, probably got that far because he didnāt take the drug he made. I doubt heāll answer emails at that age, even if we managed to get his email address.
Regarding 23andme, apparently is useful but itās complex stuff. After 1 year Iām still digesting things. I made an analysis on paper but I need to take blood samples and those are expensive because no doctor will prescribe me them as they know shit except the 10 or 20 worst diseases they studied at univ and have easy diagnostics
I love the analysis. How will you compare your samples to your theory? Regarding supplements, before I knew I had PFS, homeopathic doctor gave me b complex, zinc, dhea and d supplements. 48 hours of amazing recovery, then crash.
Hey any word back from any on the researchers? Who did you contact? We are all desperate for answers and I think targetting these studies canāt hurt, this one especially. These guys have all looked at blood samples and perhaps tissue samples of folks damaged by a similar acting drug. Maybe they have some additional data sitting somewhere they didnāt think important at the time that is telling for us. Will it lead to a cure? Doubtful but it spreads the word and may inspire some of these researchers to further former studies. I agree this was a great find.
Thereās a big old thread on cortisol management.
Just dug it up FYI as it wont show on a forum search.
Seems like cortisol management is very important, but there are people who got no benefit from supplementing it. Maybe their dosing was off or they didnāt do it for long enough. Another āone size doesnāt fit allā puzzle regarding PFS.
Did anyone buy this publication sciencedirect.com/science/ar ā¦ 6014000831?
Keen to share with my endo at next appointment if anyone has it.
I donāt have it, but this is the study they released in 2013. Would be nice if they offered course of action regarding all this mayhem.
No doctor would rightfully do this, because weād all line up and beg them to try, but after publishing an article on this, it would give us all hope if the authors theorized potential therapies that could help us. If only someone here had access and could pick their brains. So how to right these altered levels?
I believe this was the preliminary Italian study that led to the present study on PFS launched at the University of Milan by the same group of researchers. The Uni of Milan study is trying to explain the root cause of this condition. It is the most promising study to date, although the north american studies, and all other studies for that matter, will play a critical role in solving this puzzle.
Has anyone brough this study to the foundationās attention? or the Italian or American researchers?
Well, does anyone have their contact?
Here are the contacts listed in the studies:
Baylor College study: Dr.Mohit Khera (mkhera@bcm.edu)
University of Milan: Dr. Guido Cavaletti (roberto.melcangi@unimi.it)
Brigham and Womenās Hospital (Harvard): Dr. Shalender Bhasin (sbhasin@partners.org)
Sadly, we all know that 5ar fails to return to baseline. I hope once these current studies are complete researchers move on to actually figuring out how to increase / repair our enzymes. Unfortunately, there is no money involved for big pharama thatās why no treatments have been discovered
There is money for geneticist to figure out how to produce 5ar. There is a rare genetic disorder of deficiency of 5ar.
Perhaps they can turn on the gene to produce natural 5ar again in the body. This is years away but may be possible because of the advancing tech.
The last thing we want is artificial 5ar. They can already make synthetic enzymes but we should try to get the real thing.