You and your puppy.
This is what I always mean, many here think they know it better. Something that has never happend before or effects that are knowen. The effect is knowen btw and it is called Antiandrogen withdrawal syndrome. Many here seems also sadly not understand what the is the main point. The cells shut the genes down that are expressed by the AR, because the signal of the AR gets to high on the DNA. Such things are called negativ autoregulation and are not unknowen. Yes, we also have problems with neurosteroids, but also, with the prostata, the bloodflow, the nerv system itself, the gut the thyorid glad the hpta, the testicals the estrogens but this are all symptomos. Just loo at people who have SMA they do have a problem with the AR and because of that a problem with the motoneurons. This does not mean we have the same problem is is just a expample.
come on guys!
This time it is really important to stay patient… I am convinced that we will receive an update soon. Awor and his researchers need time to get the things done, that need to be done. Once there will be valid datas and scientists will start to find out what has happened to us and they will find a cure.
Don´t start war with ourselfes and awor - BRING DOWN MERCK.
True, one of Merck shoot so everyone will find out about everything.
Most of the docs don’t follow the research at all and we all know none of them are having any success with treatment. So, speculating what they believe is or is not the cause or anyone saying “I know it’s neurosteriod related” in the absence of any published data is just pointless. We all hope to have answers to those questions soon but right now it’s 100% speculation. The best thing we can do right now is support the foundation by participation in the earlier outlined studies and by financial contribution.
Your welcome to come here and do it as well…lol
How about just a simple update that says things are still in the works? Why has that update never been given? Makes me think that he might not even be actively pursuing this anymore.
Just noticed that the PFS Foundation has issued a minor update under the “Current Research Initiatives” section at top of page: pfsfoundation.org/research/
Regarding Awor’s initiatives, I am quite confident he will provide an update when there is more news to share. Last I knew, things were still in progress.
that is great news MEW, even when it seems like things are slowing down, something brand new and productive pops up, awesome, thank you so much
Think about this.
The only research projects mentioned that could even ‘see’ the root cause of PFS are numbers 5 & 6.
These havent begun yet. And IF/when they do, they will be expensive, complicated and take years to complete and publish.
And if we are lucky and they find something wrong, it will need more research to develop treatment. No doctor will be able to prescribe you an off-the-shelf remedy for post-receptor signalling epigenetic changes.
So you will have to ‘be patient’ for many more years.
I recommend seeing as many uros/endos as possible. The awareness of PFS is growing and you might find someone who wants to help. And maybe they can find something quicker!Everbody hates a troll…You hijack every thread to let people what you think and start to make war…
Honestly this sucks and I´m getting more and more sick of reading your shit. YES! Shit. You have absolutely no idea what you are talking about. You do NOTHING! NOTHING more than just attacking, you are talking of antibodys and no this has no evidence here and no evidence there. But this shows mopre and more you have no clue. More and more everbody can think you are just a crasy troll or a Merck rep. only here for sabotage. Normaly every forum would kick such guys out and yes, just look what you are doing. This is nothing more than trolling.
Nearly everything you write is totaly BS.
Wrong, just a silly statement.
AHHH, and your plans are faster? LOL Well, I just have to look in the past what you are posting. You spent the most of the time by attacking the research. So, if you know what to do, do it and not only talking about it. Go and try some immunsuppressiva. Dr. google Oscar.
Wow, good Idea!
yes…as we have seen and can see.
Oscar! STOP incite! Just go and look in other forums for sick people, have you evers seen there any updates about running research?
To All the others, yes research takes time. Whether a research about autoimmun or genetik.
No one of us has any influence of the publ. date. So, yes you need to be patient. Sadly. But it will be publ.
Oscar, start a owen blog or someting like this agains the research. Tell the world outside what you think and call yourself Prof. dr. Oscar out of the trashcan. Go out and teach the scientis in the world about what never has been proven, just because you dont know it does not mean it does never happend. Just google antiandrogen withdrawal syndrome… I would love to take the time to…add sources to every BS you are writing. But I dont have the time and anyway it is useless. Just wait for the publ. of the first publications and than shut up. But, for now stop to be a troll here and do something usefull.
Wait a minute. You can’t launch into an attack, call me a troll and a Merck rep, and then post this^. Because thats the point I was making!
Braibug, your the one hijacking threads to tell everyone their ideas, not me. But even you must concede that it is not a good idea to put all your faith in anonymous web posts - instead take advantage of the raised awareness of PFS amongst doctors.
oscar is right, so little is known of this, and there are so may interconnecting symptoms and cycles it is IMPERATIVE that we flood neuro’s and Endo’s offices even if it is just to pick their brain. You never know not only what treatment might click, but what doctor might say…wait a minute if this happens and that happens etc.
Oscar, start your owen blog and go off. Everbody can see what you are doing here and I told you this many time to stay on a topic. All you are doing here is to incite people jumping in every Thread and talk about that the research is bs and awor is wrong and it balalala. Everbody can see!
Just look here en.wikipedia.org/wiki/Troll_%28Internet%29
This is what you are, you are not only making a point.
Let me just quote you a bit:
viewtopic.php?f=27&t=6968
viewtopic.php?f=5&t=3901&start=500
there are so many… All you are doing is attaking and nothing more, what have you done so far? Like I said many times the only thing you are doing is trolling. Yo did not make a point. Yor point has another aim, or do you think the people here are so stupid?
You wrote this:
[i]"Think about this.
The only research projects mentioned that could even ‘see’ the root cause of PFS are numbers 5 & 6.
These havent begun yet. And IF/when they do, they will be expensive, complicated and take years to complete and publish.
And if we are lucky and they find something wrong, it will need more research to develop treatment. No doctor will be able to prescribe you an off-the-shelf remedy for post-receptor signalling epigenetic changes.
So you will have to ‘be patient’ for many more years."[/i]
You did not make this point the only point you make, was that all this research about epigenetic is crap… We ALL know what you think of this so stop talking BS. I never seen Awor making a thread about why the Autoimunblalatheorie is wrong. All the time you spend here is to attak the research and nothing more go out and do something and not only talk about that.
And you seems to understand something realy wrong! The researchers are not the one who print a publication. This is why I said we have no influcence of the date.
go and look whata troll do…the same you are doing.
Well, theres a difference between being a troll and posting something you happen to disagree with. Your are just making very weak ad hominem ‘crasy troll’ attacks against me because I dont like the AR theory.
The point I was making towards ‘tdd1433’ is that being patient and not doing anything is a really bad idea, because this research will take years and may not even discover anything, if it ever even happens at all. You have got to keep an open mind and do everything you personally can to find answers.
these research initiatives are nothing but 110% positive, no matter what anyone one persons opinion is, and any negativity directed toward them or the individuals involved in them, is simply foolish beyond words … i agree it would not hurt to see nuero’s and endo’s etc. and to pick their brains while raising awareness
Oscar, everbody can see what you are doing here… just look at the links and there are many more. I wote you a few times to stop to attak people and this is what I dont like, just have a look, what a troll is. I see how open minded you are.
This are the only things you can do and what you do. I never said something against that no one should look in other directions and ever awor thinks so, so if you dont like the theory or not this doesnt matter. But you use nearly every thread to tell the people what you think about it, sources are only your half knowledge and nothing more. Someone must be very very brainfogged to dont see what you are doing here in this forum and this is only to incite against this running research.
We can start a new thread, why oscar is a troll. But for now even this thread is about …see headline. I told you what I think and If you dont like make a new thread, why the oscar is a troll theorie is wrong.
What difference does it make how open minded I am? Anyway, theres a big difference between being open minded and closing your mind off to reality. I know, I’ve been there.
Brainbug, I never said anything about you. But the impression has been given that the AR theory is correct and cannot possibly be wrong.
So I’ll just repeat my point again: Not taking advantage of raised awareness and not seeking medical help, all because of some anonymous messages on the internet of unknown veracity, is really showing a lack of common sense.
Thing is… the theory may not be 100% correct. But it is likely that the deep molecular analysis that is going on with researching this theory WILL lead us in the right direction…
Oscar, I wrote you long ago a pm. Your never replyed to it. I told you we all are sitting in the same boat. If you want to raise “awarenes” about finasterid and the danger and go to doctors and tell them about it may be someone has a good idea, I have nothing against this, I do the same. But we have threads for that. You just want to raise awareness against a Thing you dont like. That you can do this is a forum, but the way you are doing it is wrong. I told you many time to stop highjack threads but you still go on. Dont say it is not like that cause everbody can read what you do. But do not only write the whole time about it, what can be done. Do it. Do something If you go and find docs, who will help you no one will jump in every therad, like you are doing it and telling people that this can be wrong and bla bla. Everthing can be wrong, but what have you done so far? You spent more time here to raise awarness against a running research than doing somthing positiv. I´m out of this discussion, because the thread will we destreoyed by such things. WE are no enemys.