Would continued hair loss during and post-fin indicate 5AR activity?

Would continued hair loss during and post-fin indicate 5AR activity?

I have no loss in libido, except for avoidance of the matter because of the stress of failure.

Fin helped me hold onto the hair I had, and seemed to decrease the rate of hair loss very well initially. But I’ve definitely lost a significant amount of hair in the last several years and in the year+ that I’ve quit.

Would this indicate 5AR activity?

Having addressed all of my sides except for E.D. via Clomid/Testim/Arimidex and testing at top of range for T and DHT in January (but still addressing resultant escalated E through Arimidex), I’m trying to exhaust all hormonal testing before commiting to a re-vascularization operation to address my diagnosed circulatory problem. I describe that here (I really recommend you investigate physical contributers to E.D, btw):
propeciahelp.com/forum/viewtopic.php?t=3427

So I’m awaiting updated labs from my pcp (comprehensive metabolic panel, lipid panel, CBC, Vitamin D 25-Hydroxy, Urinalysis, Thyroid Cascade Panel, Cortisol, Testosterone, DHT, Estrogen)…before doing my routine T / DHT/ E / SHBG / LH / FSH testing wtih Dr. G. and discussing adding more to that lab order (3adiol G or androsterone/etiocholanolone (A/B) ratio in urine, Progesterone
Pregnenolone , 17-OH Progesterone, 17-OH Pregnenolone, Aldosterone, Androstenedione, Androstenediol DHEA-s)–not sure if these are excessive or redundant.

If everything checks out normal, I don’t know what other recourse I have. It would ease my mind to know that the DHT my body was producing was being utilized.

Also, I’ve read about genital skin fibroblast testing to measure 5AR activity, but I don’t know how to go about getting this tested.

Any comments or feedback?

Considering impaired nitric oxide synthase activity in the penis is a proposed mechanism for 5ARI-related erectile dysfunction, you might want to investigate that via blood/urine or skin samples. Dr. G should know what tests to undertake to do so.

propeciahelp.com/forum/viewt … 0902#10902

These labs do genetic testing of 5AR2 enzyme but may also be able to do fibroblast tests. Call to find out.

ncbi.nlm.nih.gov/sites/GeneT … =genetests

Mew, thanks for the info, definitely going to add to the list of things to discuss.

I’ll call that lab and see what tests they do, cost, etc. & report back.

It seems as if some of the other methods for testing for 5AR activity (androsterone/etiocholanolone (A/B) ratio in urine or 3adiolG levels) might be useful enough, no?

Yes, absolutely.

See PDFs and discussion here: propeciahelp.com/forum/viewt … 3678#13678