I think you missed the point.
First of all, I was just telling people that if they start taking GABA agonists, they will just be trading in one problem for another…so this is a warning to people considering this as a treatment. You’ll end up in the same place on a benzo in 2 years that you did on propecia in 2 years. It’s guarenteed.
Second, there are about 300 pages of FAQs and studies… most of which I actually did read & GABA is only mentioned once or twice… and it’s usually referenced in a backwards or highly tangential manner. There is one study that says that in vivo (test tube) there are changes in plasticity of the gaba receptor due to a metabolite of fin and people seem to have run with this finding all over the site.
Example: “Has anyone tried Xanax or any of the other GABA increasing drugs??? It sounds like this would really help our brain fog and visual problems.”
– No, it will help in the short term and worsen everything in the long term. Read Benzobuddies.org. (Hence, my post). Furthermore, only GABAc has anything to do with the eye - and no drugs target GABAc & propecia doesnt affect GABAc (not even sure it affects GABAa based on the study posted). Finally, what happens in monkey vision doesn’t happen in human vision.
Example: From the FAQ you told me I didn’t read: “blocks Progesterone --> Allopregnanolone conversion, thus interfering with GABA-A receptor function in the brain (anxiety, possible seizures, depression)” – in test tubes, that’s nice … but the neural network of the brain is 100x more complicated. Also, GABA is not involved in depression: (ncbi.nlm.nih.gov/pubmed/2174069: “These results do not support the idea that GABAergic mechanisms are involved in the pathophysiology of depression”) I haven’t heard of anyone having a seizure while quitting propecia but you WILL have a seizure if you stop benzos overnight.
I am sure you would have undoubtably also jumped down my throat and told me to “read the FAQ” if you were posting on a hair loss forum about “considering propecia” 5 years ago and I replied “why would you consider something that has a high potential to kill your sex drive?” Sorry to be the bearer of bad news - but benzos are a nightmare. You can find out now & thank me or you can find out in 3 years when you’re addicted to them and your memory degrades to nothing.
A lot of the research cited here: propeciahelp.com/forum/viewt … light=gaba is the EXACT research that got 1000s of people hooked on drugs like xanax, klonopin, etc…for years. Most of this was in the early 90s. Now, we know that what happens in monkey brain does not translate to humans, and these are NOT good drugs to take long term. Monkeys don’t have advanced cognitive processing like we do and that is why if you read the full text of these (highly academic) studies, you will see a huge “limitations” section where they make that very clear. Anyway, you don’t have to trust me. I’ve provided two useful links about the downside of gaba agonists in my first post. From there, it’s your / your doctor’s choice.
I was asking “WHY” people are advocating this treatment because I know (from experience) it’s not a good idea. I wasn’t asking “why” in the sense that I didn’t read / understand the research.
Finally, why so bitchy? Are you going to blame propecia for that too? If “nobody has the time” then don’t reply that “nobody has the time.” Look at the time I took at 2 AM when I have to be up in 5 hrs. How ever did I find the time? You’re welcome.
