No. A disease of the AR cannot possibly explain the high percentage of prostatitis in PFS sufferers, bloody stools that many of us have, improvement with antifungals, worsening with immuno-suppressing corticosteroids such as dexamethasone (me, JG) etc ect. Utter and complete nonsense.
Guess who I’m trying to impersonate here
Is this awor?
And what the similarities, like everyone here has high out of range testosterone?
No, it’s me.
Similarities:
Gynecomastia: breast enlargement.
Impotence
Erectile dysfunction
Reduced fertility
Low sperm count
Testicular atrophy: Testicles become smaller and less functional.
Fasciculations: Twitching of muscles when at rest.
Cramps: Large muscle spasms.
Muscular atrophy: Loss of muscle bulk that occurs when the lower motor neurons do not stimulate the muscle adequately.
Differences: PFS cases seem to respond well to testosterone, but poorly to DHT. Reasons should be obvious.
Please enlighten us
Because our AR’s have become hypersensitive to DHT and not T. I thought you out of all people would know.
So you repeated the “symptom”, where is the explanation? Plus I dont understand how AR rendered hypersensitive to DHT, but not T, makes us more reactive to T vs DHT, did you mean the opposite?
huh?
So this would explain why everyone here has out of range high dht then?
Thank you for editing, and no, I did not repeat any symptoms. I listed them once here and they are available for anyone to see.
The other question is beyond my expertise, but I will give it a shot anyway.
When the DHT came flooding back, the AR gene got down regulated, making the AR unable to bind properly with DHT.
so then i would refer back to the “anonymous” comments posted some time ago from the guy explaining how to reregulate the AR
Second, why not, but another fact is that 5ar is in fact POSITIVELY controlled by DHT and adrogens in general (no negative feedback - the usual thing happening in the HPTA for instance- but the opposite, more DHT actually induces MORE 5ar). This is why some of us (including me, JN, cytochrome…) tryed andractim/proviron to increase DHT. Its did work for JN for a while so I guess he was still sensitive enough to it? Anyway, bottom line, we dont know anything here and any theory is bound to be unscientific speculation based on hints of knowledge, and many of us react so differently to hormones that its impossible to create universal PFS clear-cut laws for everyone.
You mean the 5ar2 reduced DHT, So the problem should be only in 5ar2 areas, right, so everyone should be not experiencing hair loss post fin?
And if DHT cant bind to the receptor properly like T with kennedys patients shouldnt we have high levels of DHT in the blood, like T with kennedys patients?
Also i like others on this board crashed while on finasteride, never to make any sort of brief recovery, that hardly says dht hypersensitivity to me.
This is absolutely spot on.
I don’t know but high DHT has been reported by members on the forum.
edit-also most people’s bloodwork/dht level is taken coming off the drug, so their levels are still low. People who report high DHT might be the ones months/years off the drug. Mew’s DHT was nearly out of range high 19 months off.
mypropeciasideeffects.com/my-finasteride-hormones-comparison.html
Finally, right, you don’t know. So please stop writing stuff like you do know anything for sure, what is true and what is false.
That’s your interpretation of my posts, I never said I know for sure. I use proper qualifiers like “seems to be” “I think…” “probably”
Another out of range high DHT level 1 year off the drug:
Dihydrotesterone 205-990 pg/ml N/A 1627
Bold 1 year off, red, 1 week off.
Maybe we need to comb over the hormone section and see if we continue to find this pattern.
edit
Another high DHT (2 years off)
Dihydrotestosterone 4271 (HIGH) 860 - 3406 Pmol/L
Maybe a thread of its own is warranted.
edit
another one
DHT 6063 range Male: 860-3406 pmol/L
This is getting interesting…
finsucks
almost out of range high (7 years off)
DHT 433 ng/l (94-476)
Well I’m done with you, since your intellectually dishonest and a hypocrite. Its not difficult to see in your post history (ie in IHP’s thread) where you categorically assess sentences such as “No. This can’t possibly be the cause of blah blah blah” or “Utter and complete nonsense. Blah blah” in response to people ideas and theories.
I can think of about three or four out of about, well most of the blood tests on this forum, % wise maybe less than 5.
Also you keep banging on about sperm count, there is only on there with a low count, my count is fine also, the problem seems to be more to do with Sperm motility.
But anyway if you want to play this little game then…
DHT: 392 pg/mL (106-719) a year off
dht 676 250-990 4.5 months off
DHT - 31 [25 - 75] ng/dL 4 years off
DHT 1.58 nmol/L (1.13 - 4.13) at least a year off
DHT 24 ng/dl (25-75) years off
DHT - 52 (30-85 ng/dl)
DHT: 63 (25-75)ng/dl
DHT - 3.6 (0-13)
DHT 16 (0-13)---------OMG stop everything
DHT - 27 [25 - 75]
DHT - 22 (25-75) 4 years off
That was after 4 pages, i think your on to something, 1 out of 11, kennedys disease is more like 11 out of 11
links?
Try the search button or the blood test section,
Still no one from the hypersensitivity camp touches this on.