This is a common misconception on this forum. If you experience a recovery that turns out to be temporary, your system has not “reset”, but has moved to a different state.
Example (on me, and possibly, UK20):
- My endocrine system is in state A
- I take pregnenolone and experience an almost full recovery within a day. My endocrine system has moved to state B
- Within 5 days, the improvement has weened off, pregnenolone doesn’t work anymore, and I feel (almost) exactly how I felt in state A. But at this point I am not in state A, I am in state C.
At the end of step 3, even if I feel like in state A, I cannot be in state A. If I was in state A, then I could improve for 5 days by taking pregnenolone, which is not the case (hope it makes sense). And if you think about replying “maybe you develop a tolerance to pregnenolone”, Dr Crisler says that this doesn’t make sense.
In my particular case, blood tests and a saliva test show that the set back was caused by an exhaustion of my thyroid hormones, due to an increase of cortisol obtained via pregnenolone supplementation.
The bottom line is that, when you experience a set back, it is not a step backward, but a step forward. So don’t be frustrated if you feel that something “stopped” working. It most likely hasn’t stopped working; it still works, but your system is trying to get back to the (bad by stable) loop it was in.