very high prolactine very low TTesterone, realy life story

General Discussion
#1

I met a guy in real life few days ago.
The guy has a pituitary tumor and very high prolactine close to 400 ng/mL which is very very high and his total testosterone is 2. yes only 2. He has been on Agel for the last four months and applying 10 pumps a day, again very high dose and his TT moved to only 4 in four months. Now why

1- his TT was only 2. I think his high prolactine saturated his Androgen Receptors. what do you think?
2- why Agel is not working just like us. Is it absorption issue?

He is just like us. joint pain, head ache, low energy etc etc. but does not have any gynecomastia.

Please express your thoughts. Is it possible our body has produced unknown/undiscovered protien which is working the same way as prolactine is working here.

#2

Hey,

he may be has nearly the same symptoms but the root of is problem is a tumor. The idea, wiht the proteine is not bad, but we more have a lack of some proteins. Some more some less…

#3

the interesting thing despite very low testosterone this guy does not have any gyno( I saw him his top clothes removed ). We have been thinking gynecomastia is caused by bad T:E ratio but why this guy does not have it but we do despite better testosterone.

#4

Yes, your thoughts are not wrong. The Problem is not the E:T ratio the Problem are also not low T levels or high E levels. The Problem also has nothing to do with any kind of autoimmun problems.
We have neuroligical damages, penile tissue damages, Prostata tissue damages. Every tissue that depends on the expression of genes controled by the AR. Yes also neve cells, just look at people with SMA or KD. Sadly we can not realy compare us with those guyes, or guys who have a TU.
see Hormon---->rezeptor---->Gene—>transcription---->translation—>product.
If the cells do not resond well to androgens anymore, but still respond to E …it doesnt matter, how high or low the E or T is. E will run normal as before but the androgenic action is missing. I see, you more and more get behind all this. : )

#5

Can you expand or cite references please. I’m intermittently trying to follow all this.