Valerian root

Anybody ever tried this? Apparently it’s supposed to affect GABA receptors.

anxiety-and-depression-solut … lerian.php

i ve read it,but i dn t understand…could it be good in our case?

Here is a blurb from the article. Valerian apparently helps soothe anxiety/nervousness b/c it’s replete with GABA.

Valerian has an affinity for GABAA receptors, likely due to the relatively high GABA content in valerian itself. The amount of GABA present in valerian extract is sufficient to induce release of GABA in synaptosomes and may also inhibit GABA reuptake.

Other believed mechanisms of action in valerian include inhibition of the catabolism of GABA by valerenolic acid and acetylvalerenolic acid and affinity for the 5-HTA receptor by another constituent of valerian, called hydroxypinoresinal.

Due to the herb’s historical use as an anti-convulsant, sedative, migraine treatment and pain reliever, most basic research has been focused on the interaction of valerian constituents with the GABA neurotransmitter. The findings of these studies remain inconclusive. Thus, the true mechanism of action of valerian remains unknown.

I’ve already posted under another section, but here goes again…Valerian works, but you have to use enough of it. You can get it here, along with other soothing herbs. ethnosupply.com/ I use it occasionally mixed with kava kava and the combo seems to work well.

seems to work for wich side?

Anxiety and restlessness

Is it a short term fix i.e. several hours or a long term fix?

Short term

the effects lessen over time