Someone tried ?
- Trichosantheskirilowii (TK), Asarumsieboldii (AS), Sanguisorbaofficinalis (SO), and Xanthium strumarium (XS) enhanced the proliferation of 22Rv1 cells without having cytotoxic effects.
- TK, AS, SO, and XS increased androgen receptor (AR)-induced transcriptional activity.
- TK, but not AS, SO, or XS, produced a significant inhibition against AR-binding activity.
- TK treatment positively regulated mRNA expression of the AR-related molecular targets prostate-specific antigen and kallikrein 2.