Trazodone and Aricept

Therapeutic Efforts Pharmaceutical
#1

My first post to the message board. Short background: Took fin for 2 years. At the end of 2 years my sex drive started to fall off. I stopped taking the fin and it was like a spark in me went out. Before that day I had never taken an ED drug. Since that day I have had to use ED drugs almost exclusively to have sex. It has been about 2 1/2 years now since I stopped fin.

Like everyone else on this board my bathroom cabinet is full of all kinds of stuff that I have tried to get my sex drive back. Most of it hasn’t been too helpful. There is one thing that I would like to share with the board though. Last year my doctor prescribed Trazodone for sleep. It is an older (not SSRI) anti-depressant that is often prescribed for sleep. I started out at a very low dose (25 mg) which the prescription stated could be increased to 150 mg as req’d. I stayed at 25 mg. About a 1/2 hour after the 2nd dose (on second day of use) I got a very strong erection. My sex drive improved tremedously, and I had basically a normal sex drive and did not need ED drugs for about the next 3 months. Then as bad luck would have it I seemed to develop a tolerance to it and it quit working. Last fall I quit taking it. Then after about 4 months off it I tried it again and my sex drive improved for about 10 days and then nothing. In order to try to prevent tolerance I am currently taking 25mg twice a week (Thursday and Friday) to get my libido up for the weekend. It helps alot. I get some good nighttime erections, but still need ED drugs to have sex. I would recommend it to anyone for at least a try. It is cheap. I got 90 100mg pills for $5 from my HMO. It does make me a little fuzzy the next day but not too bad for an anti-depressant. It also helps me sleep.

I have seen several posts on this board by people who stated that they were taking Valium due to the anxiety of this condition. Valium has well known ED side effects. Try Trazodone instead.

I was thinking trying to platoon Trazadone with another drug that had increased libido side effect. Saw in this link that Aricept can in some instances increase libido. Has anyone tried it?
answers.google.com/answers/threa … 02711.html

I also saw that someone had used Adderall with some luck. Maybe I will try that. I am also convinced that this is a neurotransmitter issue. My guess is that the Trazadone is stimulating some part of the brain that the fin damaged.

Anyone else have a recommendation for a drug that has a libido increasing side effect? Thanks.

#2

boost-your-low-testosterone.com/index.html

#3

Thanks for the link. Have you tried any of the supplements on it that seemed to work?

As an aside I received my first shipment of generic Aricept yesterday. I only ordered the 5mg (low dose) to give it a try. Being skeptical about brain chemistry drugs my first dose last night was a 1/4 of a 5mg tab. Initial indications are positive. All I took at bedtime was 25 mg of zinc and the Aricept. Had strong night time erections and woke up with an erection. Also seemed to get aroused easily during the day. Will give future updates if it turns out I can actually have normal sex without ED drugs (my goal).

#4

I have not tried any of them yet, no. The author of that site is also a member of this site now. He does a very good job at giving his experiences with each one of those supplements.

#5

Italysideffect ask me to post my Aricept results so here they are. Took 1.25 mg/day for approx 14 days. First 10 days were like gangbusters, hornier than a high school kid. Then got some semi serious side effects, that lasted for 3-4 days. Lots of general nausea, and a real tight feeling in my chest. Also a kind of hard to describe feeling in my head, not bad, just different. I was very clear headed and it seemed even though I was having these side effect that my sense of humor improved.

Anyway after the 14 days or so I couldn’t take it anymore so I haven’t had any in 10 days or so. Even so I can still feel the improvement in my sex drive. Current plan is to take 1.25 mg every 3 days to see how that works. Per wikipedia the half life of this stuff is 70 hours, so a little goes a long ways.

The “normal” dose for alzhiemers patients is 10mg per day of this stuff. All I can say is if you take 10mg a day of this stuff you are going to be seriously wacked out!

#6

Badluck,

Why not take dopamine instead of trazadone. Dopamine and Prolactin are both normally present in the human body and the two play off of each other. If Prolactin levels get too high Dopamine levels can get excessively low.

Did you try dopamine already? I don’t know much about trazadone, except one article I read about it. So correct me if I’m wrong, but Trazadone is an antidepressent right? So it’s not normally present in the human body.

#7

Bostonusa - I have not tried dopamine. I did consider it but I’m not sure what to take. Trazadone is an anti-depressant. I have read on one site that it is supposed to raise dopamine levels. It is the only thing that I have taken that increased my sex drive to near normal levels…that is until it quit working. I am not currently taking it.

I did consider ordering ropinirole, which is a dopamine agonist. Here is a link to what it is:
netdoctor.co.uk/medicines/100002252.html

It is available on the internet for fairly cheap:
edmedsnow.com/search.php?sea … =7&I1.y=12

I’m getting kind of tired of trying different stuff, but I might consider it. Good luck to you.

#8

I took requip for a few weeks…sex drive did increase a bit, but i started having some side effects…got very nautious, and had to stop taking the drug…

The more I think about it, The more i believe propecia messed with our nervous systems…anyways BADLUCK I think you may want to check out L-Deprenyl

deprenyl.org/

I’ve heard good thing about it…This maybe a solution for some of us…or maybe not, but if you don’t try, you will not know…

…Seeing Dr. Crisler in a few months…

Later

#9

Thanks for the feedback on requip. The article on deprenyl was interesting however I didn’t understand the following comment:

"one will bring out the best of deprenyl only in combination with other specific pharmacological agents. Without this knowledge, buying deprenyl may just be a waste of money. Or a dangerous experiment. "

What “other specific pharmacological agents” is he referring to?

#10

I think he saying combining it with other drugs could be dangerous…Do some more research on it…It’s suppose to be a good anti aging drug if taking properly under medical supervision as well…

Bodybuilders take it as well i believe…I’ve read info on it in bodybuilding forums…

Guys think…do research…talk to your respected doctors and see what they say…Ones that will LISTEN TO US! Arrogant doctors are pieces of crap, they don’t listen,and they should have their medical licenses revoked. Good doctors listens to their patients very closely, diagnose the problem and try to treat it to the best of their ability…Not by making false and LAZY assumptions…

IF YOUR A DOCTOR and HAVE DISMISSED PROPECIA FROM SEXUAL SIDE EFFECTS and are TELLING PATIENTS IT’S in their HEADS, PLEASE READ EVERY POST ON THIS BOARD BEFORE YOU DO THAT.

#11

Trazodone (Desyrel, Beneficat, Deprax, Desirel, Molipaxin, Thombran, Trazorel, Trialodine, Trittico) is a psychoactive drug of the piperazine and triazolopyridine chemical classes that has anti depressant anxiolytic, and hypnotic properties.[1] It has been advertised that its therapeutic benefits become noticeable within the first week of administration. Trazodone has considerably less prominent anticholinergic (dry mouth, constipation, tachycardia) and sympatholytic (hypotension, sexual dysfunction consisting of erectile dysfunction and anorgasmia) side effects in comparison to most of the tricyclic antidepressants (TCAs) and tetracyclic antidepressants (TeCAs).

Donepezil (also misspelled donezepil), marketed under the trade name Aricept by its developer Eisai and partner Pfizer, is a centrally acting reversible acetylcholinesterase inhibitor.[1] Its main therapeutic use is in the treatment of Alzheimer’s disease where it is used to increase cortical acetylcholine. Its binding to the acetylcholinesterase can be seen at Proteopedia 1eve. It has an oral bioavailability of 100% and easily crosses the blood-brain barrier. Because it has a half life of about 70 hours, it can be taken once a day. Initial dose is 5 mg per day, which can be increased to 10 mg per day after an adjustment period of at least 4 weeks.