Tourette-like tics vanish in mice treated with histamine - Yale News

Searching muscle spasms or twitching brings up 50 plus results.
Ive brought this up myself a few times feeling I might have worsened spasms when taking a h1 blocker or histamine degrading bacteria, so this might be worth mentioning.

Tourette-like tics vanish in mice treated with histamine

Histamine’s role in immunological reactions such as allergies has been intensively studied, but in recent years the neurotransmitter histamine in the brain has been linked to a variety of conditions, such as Parkinson’s, multiple sclerosis, autism and obsessive compulsive disorder, as well as Tourette syndrome.

Interactions of the Histamine and Dopamine Systems in Tourette Syndrome

Tourette syndrome is a neurological disorder that affects many children and adults. It is characterized by stereotyped involuntary movements

Histamine Regulation of the Basal Ganglia and the Pathophysiology of Tics

http://grantome.com/grant/NIH/R01-NS101104-02