Took an antidepressant years after finssteride

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What specific drug did you use (finasteride, dutasteride, saw palmetto, isotretinoin/Accutane, fluoxetine, sertraline, citalopram, leuprorelin, etc…)?

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How long into your usage did you notice the onset of side effects?

What side effects did you experience that have yet to resolve since discontinuation?

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Sexual
[ x] Loss of Libido / Sex Drive
[X ] Erectile Dysfunction
[ ] Complete Impotence
[ x] Loss of Morning Erections
[ x] Loss of Spontaneous Erections
[ c] Loss of Nocturnal Erections
[ ] Watery Ejaculate
[ ] Reduced Ejaculate
[ ] Inability or Difficulty to Ejaculate / Orgasm
[ ] Reduced Sperm Count / Motility

Mental
[ ] Emotional Blunting / Emotionally Flat
[ ] Difficulty Focusing / Concentrating
[ ] Confusion
[ ] Memory Loss / Forgetfulness
[ ] Stumbling over Words / Losing Train of Thought
[ ] Slurring of Speech
[ ] Lack of Motivation / Feeling Passive / Complacency
[ ] Extreme Anxiety / Panic Attacks
[ ] Severe Depression / Melancholy
[ ] Suicidal Thoughts

Physical
[ ] Penile Tissue Changes (narrowing, shrinkage, wrinkled)
[ ] Penis curvature / rotation on axis
[ ] Testicular Pain
[ ] Testicular Shrinkage / Loss of Fullness
[ ] Genital numbness / sensitivity decrease
[ ] Weight Gain
[ ] Gynecomastia (male breasts)
[ ] Muscle Wastage
[ ] Muscle Weakness
[ ] Joint Pain
[ ] Dry / Dark Circles under eyes

Misc
[X ] Prostate pain
[ ] Persistent Fatigue / Exhaustion
[ ] Stomach Pains / Digestion Problems
[X ] Constipation / “Poo Pellets”
[ ] Vision - Acuity Decrease / Blurriness
[ x] Tinnitus (ringing or high pitched sound in ears)
[ ] Hearing loss
[ ] Increased hair loss
[ ] Frequent urination
[ ] Lowered body temperature

[ ] Other (please explain)

What (if any) treatments have you undertaken to recover from your side effects since discontinuation of the drug? None

If you have pre or post-drug blood tests, what hormonal changes have you encountered since discontinuing the drug (please post your test results in the “Blood Tests” section and link to them in your post)?

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Tell us your story, in your own words, about your usage and side effects experienced while on/off the drug.

Years ago I had pfs for a while after stopping fin
Ot wasn’t that bad un that I ecovesd within a year ir twi naturally

Following a period of stress I took an antidepressant and have since had a bad crash and lost muscle as well as libido. It’s much worse than the pfs crash

I didn’t know about “pssd” or whatever its called. I k ow they had potential long term sexual sides but I have been surprised to see the PSSD full spectrum of sides on that reddit and social.media. pssd wasn’t a thing when I had pfs, at least that I noticed.

Reading here and elsewhere its seems that having had pfs before made me more vulnerable.

Idk what to do, my t levels are in range and urologist didn’t help. I feel worse after ejaculations etc. I also can’t get drunk. I never knew this was a symptom

Can simeome tell me, are pfs and pssd the same thing?

Why can’t I react to substances anymore and what has this to do with AR overexpression?

Self-reporting template - ONLY USE FOR FUTURE POSTS TO REPORT ANY TRIALS OF TREATMENTS, NOT YOUR INITIAL MEMBER STORY

  1. Name of the therapy/substance:
    • Dosage:
    • How often you took it:
  2. Status
    • Still using [ ]
    • Stopped with no lasting change to initial symptoms [ ]
    • Stopped with persistent change to symptoms [ ]
  3. Duration of use: Days [ ] Months [ ] Years [ ]
  4. Response when you started:
    • Greatly improved [ ]
    • Slightly improved [ ]
    • Stayed the same [ ]
    • Slightly worsened [ ]
    • Greatly worsened [ ]
  5. Current response (if you’re still using the therapy/substance) OR Response in the time before you stopped the treatment
    • Greatly improved [ ]
    • Slightly improved [ ]
    • Stayed the same [ ]
    • Slightly worsened [ ]
    • Greatly worsened [ ]
  6. Lasting changes to initial symptoms after cessation (if you have stopped for more than 3 weeks)
    • Greatly improved [ ]
    • Slightly improved [ ]
    • Stayed the same [ ]
    • Slightly worsened [ ]
    • Greatly worsened [ ]

I had mildish pfs that went away after a year or so about ten years ago.

In that time I remember people on here taking remeron aka mirtazipine for sleep. Now I read that drug alone cam crash people like pfs.

Can someone explain why substances no longer exert any effect? How does this tie in with the AR overexpression theory? It seems like brain damage.

I can also bo longer get a rush from music. It feels like dopamine has been turned off. I never had these symptoms with pfs, I think I briefly had the loss of feeling from music but it went away and I attributed it then to depression.

Could you fill in some extra info, in the first post, the name of the antidepressant, etc please?

In answer to your question, we see significant overlap with PSSD patients. Until we know more, it’s impossible to say the conditions are the same but you might take a “walks like a duck, quacks like a duck” attitude to it.

I remember when I first had pfs and lost enjoyment in a number of things, including music. With time, this has come back to me.

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They share the estrogen receptor dysfunction