This is not a joke (vitamin A)

General Discussion
#1

Ok I’ve experimentally consumed approx 10million IUs of retinyl palmitate (vitamin A) over about 8 months and my retinol blood work is still in the normal range only a slight increase. It was initially low normal. Thought I’d move it up a bit but as described took alot of pills to do it.

Is this medically possible? Shouldn’t I be well above normal range, or a least top of range with the huge dosage?

I get retinol is tightly regulated but I must have maxed out my liver stores now, right ? Have been sure to take it with fat, etc.

Also I know it’s toxic, my liver is fine but my kidney function has dropped a little. So I’m not recommending anyone do this, but I’m under doc supervision.

Curious if anyone here has a idea why retinol levels in previously used accutane user is so hard to move or is this normal for all mankind?

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#2

Don’t have any medical inputs for you but how are you doing now @Calcified?

#3

I’m ok.

#4

How about PAS?

#5

Im still trying to grasp the whole vitamin A thing now, my levels drop pretty quickly without supplementation. It’s still a huge mystery.

Honestly if I went anti A I reckon I would be depleted in a few months.

But I may be wrong I have no medical training but Alcoholics have low retinol so maybe it’s a liver issue, still a guessing game, unfortunately.

#6

Update! kidney/liver function all good now, currently taking lower vitamin A dosage but retinol levels unfortunately dropped back to low normal.

Still wondering if this is normal.

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#7

I meant did you notice any improvements in post isotretinoin syndrome, if you had it

#8

Vitamin A is interesting. I was under the impression that my liver retinol was low so I guzzled beef liver for months. I think serum Vitamin A isn’t an accurate measurement since it’s stored in liver and fatty tissues. I used symptoms as an indicator. I noticed my skin was getting drier than usual and exfoliating. My hair loss also seem to be accelerated. Last but not least, my allergic reactions got worse and excess Vitamin A may also cause this. These are possible symptoms of high vitamin A so I stopped.

High Vitamin D lowers Vitamin A or so I heard. Did your check yours?

#9

I’m not encouraging anyone to take as it is toxic but I’m monitored by a doctor and it has help my skin issues.

#10

My vitamin D is normal.

#11

you havent PAS yet, you know about PAS but you continue accutane ha ? Omg. Why did this disease find me when there was so crazy people.

#12

No I don’t continue accutane, don’t know what your saying, PAS involves skin problems as well.

#13

you have already skin problems right ? you taked accutane for this. how come PAS contains skin problems ? You have skin problems already before accutane

#14

Yeah PAS is skin, stomach issues, weight gain, low testosterone, mental health, joint problems basically anything that RA does in the body, um…maybe everything.

Isotretinoin interferes with endogenous vitamin A metabolism in the skin.

#15

Update, latest retinol results while taking palmitate/vitamin A 50,000iu daily.

1.8 range (.9-3.00)

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#16

I would be careful, blood levels might not reflect intracellular levels.

#17

They go up when I hit closer to 100,000 iu daily, skins a little drier on 50,000 iu but really best benefits are above that level, but I realise its not recommended, but I had a huge dose and duration of isotrention at 16. My skin went from peeling chunks of pastry to normal while on it. Maybe I adapted.

Doc thinks my bodies response has been altered by accutane / isotrention.

Sort of weird how some people have high vitamin A without supplements.

#18

idk those are some pretty high doses, vitamin a supplements gave me eye floaters.
Accutane didnt.
I have something im going to post on this.

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#19

Remarkably my other test results are good, liver good, low cholesterol 4.1 which I was surprised. As you know i have taken supplements for over a year.

#20

Update, latest retinol results 1.5 range (.7-3)

Still consuming 50,000iu daily

Crp has gone high.

Still confused as to why retinol stays same and is sometimes lower.