Wow, i am ecstatic… i just found out what may be the main cause of my problems, just don’t know how to treat it yet. This theory may have been posted before i apologize if it is no news, but due to depression i don’t come here often. Please read about OXYTOCIN and VASOPRESSING as these hormones produced by the Pituitary might be the cause of our braing fog, orhostatic hypotension (VASOPRESSIN) and lack of spontaneous erections (oxytocin)
This is not a diagnosis made from a doctor as no one believes me as my test results come pretty normal except FSH and LH that always come low. I KNOW this is the problem with me, never felt sure about the DHT theory (and don’t discard it may have a role as well), but this makes way too much sense.
Please read this, it is like describing myself, from lack of libido to “diabetes insipidus (not related to diabetes melitus)” , to lack of sense of well being, it is all there!!!:
en.wikipedia.org/wiki/Hypopituitarism
en.wikipedia.org/wiki/Oxytocin
First how i feel:
- No spontaneuos erections (T range in 600)
- No libido
- Major depression
- behavior changes: agressiviness, no trust in anybody, no conection to anybody.
- Bloating
- brain fog
Hormones produced by Pituitary:
ANTERIOR PITUITARY
- ACTH (comes in range on my results)
- TSH (comes in range on my results)
- PROLACTIN (comes to high on results)
- Growth Hormone!!! (i never tested it, and thought it s role was only related to youth and cell renovation, but no, it is linked to glicemia in this way - hyperglicemia inhibits GH production - maybe our level is lower than what it used to be, and it might explain in part why we don’t feel well eating a lot of sugar.
- ENDORPHINS !!! READ THIS : “Endorphins are endogenous opioid polypeptide compounds. They are produced by the pituitary gland and the hypothalamus in vertebrates during strenuous exercise [1],[2], excitement, and ORGASM[3]; and they resemble the opiates in their abilities to produce analgesia and a sense of WELL-BEING.” So this is why i feel my orgasm doens t FEED my brain… When i ejaculate, the prostate does not send enough stimulus to the Pituitary and it may not produce enough endorphin giving me well being. BUT, when i run, i get some of that well being, so i feel the prostate is involved in the orgasm issue. About the running issue, this is the only time i feel more like my self, after i run for about 30 min. It is well known that running produces endorphins, event known as “Runner’s high” So the Pituitary is not producing enough endorphin on a regular basis as it used to do, unless i STIMULATE it, by running.
FSH and LH (always come very low on my results):
What i never understood is how come these hormones come low (1.2 on scale from 1 to 10) and my t comes normal range. This might explain it and might explain Adrenal Fatigue as well. Some of that Testosterone may be being produced by my ADRENAL GLANDS, yes, i never thought this is possible but it is. In this effort to compensate the lower t production from my testes (wich are not being stimulated from the Pituitary by LH) you wear out your adrenal glands. Also, if as some of your T now comes from your Adrenals you feel much less libido, cause the adrenal is highly involved in sugar and carbohidrate metabolism. It is too much for your Adrenals at the same time! So it takes priority in digestion and you have no libido!
but the real surprise for me is here:
OXYTOCIN (produced by the posterior pituitary):
“Recent studies have begun to investigate oxytocin’s role in various behaviors, including social recognition, bonding, anxiety, trust, and maternal behaviors. OXYTOCIN is known to act as a NEUROTRANSMITTER IN THE BRAIN”. Does that explain brain fog or what?
“Murphy et al. (1987), studying men, found that oxytocin levels were raised throughout sexual arousal and there was no acute increase at orgasm. [4] A more recent study of men found an increase in plasma oxytocin immediately after orgasm.”
Actions of oxytocin within the brain
Sexual arousal. Oxytocin injected into the cerebrospinal fluid causes spontaneous erections in rats,[9] reflecting actions in the hypothalamus and spinal cord. (this is why we feel no link with our penis!!! it is missing oxytocin in the blood and spinal cord doesn t get it!!!)
What about this:
ADH, ANTI DIURECT hormone (produced by posterior pituitary) also know as VASOPRESSIN
That explains bloating and changes in blood pressure and headaches.
IT IS ALL HERE, All the symptoms relate to THE EXACT SAME hormones produced by the Pituitary.
Now, the explanation why the Pituitary isn’t realeasing proper amounts of hormones: Finasteride induced abnormal levels of Testosterone by blocking the conversion from t to dht. This, disrupted the HPTA axis, just as what happens to a bodybuilder. The difference from us to a body builder who has hypogonadism is the extent of damage. Bodybuilders take hormones in Cycles like a week flooding the body with external T then months of rest. We were inducing a high level of T for WEEKS or MONTHS and then the body interpreted this as the pituitary is sending too much hormones to the testes, “let s lower production of LH”. When that happens, the HPTA axis is broken or damaged FOR GOOD. I believed mine is damaged, that is why i still have "normal T’ (i am sure it used to be higher before). Second part: Body builders take T in cycles, so that does not stress the Pituitary as much as what happened with us. So their T production might be slightly reduced, but the gland still produces Oxytocin and Vasopressin in regular amounts, so that is why our syptoms differ from a bodybuilder. FINASTERIDE PRETTY MUCH BURNED OUR PITUITARY GLANDS, SO WE HAVE LOWERED ENDORPHINS, OXYTOCIN, AND VASOPRESSIN. This was actually a defense from the body, just like in an eletric wiring, when it overheats one button shuts down to protect the whole system.
WHEN WE QUIT FIN, IN AN EFFORT TO REGAIN HOMEOSTASIS, OUR ADRENAL GLANS are the ones that were over stressed. So we had panic attacks and burts of anger as the cortisol production was jumping high and low.
I can’t believe no endocrinologist could see this. It is too obvious! The problem is much simpler than we think. It is no poisoning, no DHT gene, it is OXYTOCIN, VASOPRESSIN AND ENDORPHINS. For those with more severe cases, it includes testosterone too, if the HPTA AXIS was completely destroyed.
And OXYTOCIN can be replaced, there are drug in the market for this. I am going to follow this track, the details might be wrong but it seems too obvious to me.
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