The microbiome is an important regulator of GABA, which has implications for major depressive disorder

Since we’ve been on the subject a little bit, everyone else’s favorite subject.
Not really alot here on this specific write-up, other then a quick example and possibility.

https://stm.sciencemag.org/content/11/473/eaaw0528

With this study, we can now move from correlative studies of the microbiome in depression and suggest discrete mechanisms through which bacteria can elicit changes in neurologic function. Future studies will need to assess if and how GABA-active microbes modulate phenotypes in model systems as a prelude to human studies in patients with depression. Similarly, it will need to be determined how alterations in GABA production in the intestine might translate into functional changes in the brain.