The Mayo Clinic's timeline for men taking Feminizing Hormone Therapy

This is what the Mayo clinic says to expect for transitioning men using feminizing hormone therapy. In particular, taking spironolactone or Gn-Rh (T-blocker) and Estrogen. Note, Estrogen is started 1-2 months into the process, which could similarly delay the timeline.

I’m curious, does this timeline correspond at all to your PFS symptoms?

  • Decreased libido. This will begin one to three months after starting treatment. The maximum effect will occur within one to two years.
  • Decreased spontaneous erections. This will begin one to three months after treatment. The maximum effect will occur within three to six months.
  • Slowing of scalp hair loss. This will begin one to three months after treatment. The maximum effect will occur within one to two years.
  • Softer, less oily skin. This will begin three to six months after treatment.
  • Testicular atrophy. This will begin three to six months after treatment. The maximum effect will occur within two to three years.
  • Breast development. This will begin three to six months after treatment. The maximum effect will occur within two to three years.
  • Redistribution of body fat. This will begin three to six months after treatment. The maximum effect will occur within two to five years.
  • Decreased muscle mass. This will begin three to six months after treatment. The maximum effect will occur within one to two years.
  • Decreased facial and body hair growth. This will begin six to 12 months after treatment. The maximum effect will occur within three years.

As a recent sufferer, this list kind of tell me to not get complacent with symptoms reprieves and prepare mentally for things getting worse over the course of 1 year+

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Some people get worse, some get better, some stay the same.

Trans timeline are not predictable of our path.

Different conditions.