This is a very interesting work! I may assume what it somehow restoring the neurosteroid level because both chronic stress and chronic ethanol consumption lead to decreased allopregnanolone levels. It can be something.
There’s a lot of exciting stuff coming out in a couple of years
It seems HDAC inhibitors are strong receptor-upregulators. E.g. Sodium Butyrate, a cheap and readily available one:
It would be nonsense to underestimate these effects or take into account only some pet-theories (which are supposed to have systematic effects, unless they become dubious themselves).
Could you tell me more about them? Just a brief
Take a look at all the posts I’ve made in science section
Sorry I don’t have it all memorized off top of my head