The curse of Saw Palmetto

General Discussion
#1

Hey Guys who used propecia should be happy that did not use SP. I am unfortunate one though

reade the following links.

Saw Palmetto may actually be Harmful to your Prostate

Three recent scientific studies, surprisingly indicated that saw palmetto may actually harm your prostate health! These studies, which were investigating the effect of saw palmetto on prostate tissue all came to the same conclusion: Saw palmetto has an effect similar to chemotherapy on prostate cells - it kills both unhealthy and healthy cells!
One study published in Prostate (2000 Nov) examined the effect of saw palmetto on stroma cells (the framework cells that build supportive tissue) and on epithelial cells (those which line the glands and ducts of the prostate). The study was done on normal prostate tissue and on BPH tissues from patients treated with and without the saw palmetto. The conclusion was that saw palmetto damages the nuclear and mitochondrial membranes, and causes cellular death in the epithelium and stroma.

Another study published in the Journal of Urology (2000 Nov) investigated the effects of saw palmetto on primary cultures of fibroblasts (cells that produce connective tissue), and epithelial cells from the prostate, epididymis (the tube that provides for the storage, transmission and maturation of sperm), testes, kidney, skin and breast to determine if the action of saw palmetto is selective and specific to prostate tissue. This study concluded that saw palmetto caused damage and death in prostate tissue, though there were no similar changes observed in other types of cells.

A third study published in Prostate (1999 Sep) examined the effect of saw palmetto on benign prostatic hyperplasia (BPH). Again, the results showed there was widespread damage of intracellular membranes, including mitochondrial and nuclear membranes in both healthy and overgrown prostate tissue.
In light of this new information, it seems prudent to avoid saw palmetto as a treatment for BPH. It is possible that research may eventually show saw palmetto to be an effective way to kill prostate tumor cells, but its toxicity to healthy prostate cells is reason enough to be concerned about taking saw palmetto daily as a either a treatment or preventative measure for BPH.

#2

If you’re going to post citations from articles, provide the links to original source article.

#3

i think we are all up shit creek bro, doesn’t matter what kind of boat your in as long as it is smaller than it should be and in danger of capsizing

#4

I am angry. I have no respect for so called Herbalists and doctors like Ray Sahelian and other . They are just money hungry machines who are writing books which tout the benefits of herbs, but do not give any warnings or shed any lights on the negative effects of these herbs. This is very sad. I have collapsed. This world is full of so many liars who do not care about the lives of other people. I sent email to him and he acknlowldged that SP causes the problems I am having.
Guys I am so depressed my life has ruined. I talked to Health Canada but their attitude is indifferent. If I go to court how would I prove that what I am going throug is due to SP when Doctors are not beliving it.
I am writing these all in the hope that I will save lives of many males who visit this website. I wish I had done some deep research. I did some research but thousand of websites were singing the benefits of this sinister herb, only few gave some warning.

#5

the study was cited by company Prostate miracle at. if you go on this website you will see this.

prostate-miracle.com/saw-palmetto.html

The selectivity and specificity of the actions of the lipido-sterolic extract of Serenoa repens (Permixon) on the prostate.
Bayne CW, Ross M, Donnelly F, Habib FK.

Prostate Research Group, University Department of Oncology, and the University Department of Pathology, Western General Hospital, Edinburgh, Scotland, United Kingdom.

PURPOSE: To investigate the effects of the phytotherapeutic agent, Permixon®, on primary cultures of fibroblast and epithelial cells from the prostate, epididymis, testes, kidney, skin and breast and to determine the selectivity and specificity of the action of the drug. MATERIALS AND METHODS: All primary cultures were examined by electron microscopy before and following treatment with Permixon® (10 microg./ml.). In addition the apoptotic index was assessed by flow cytometry employing propidium iodide as a fluorophore. The impact of the drug on 5alpha-reductase (5alphaR) isoenzymes was also tested utilizing a pH specific assay. RESULTS: There were changes in the morphology of prostate cells after treatment including accumulation of lipid in the cytoplasm and damage to the nuclear and mitochondrial membranes; no similar changes were observed in other cells. Permixon® increased the apoptotic index for prostate epithelial cells by 35% and 12% in the prostate stromal/fibroblast. A lesser apoptotic effect was demonstrated in skin fibroblast (3%) whereas none of the other primary cultures showed any increase in apoptosis when compared with the controls. Permixon® was also an effective inhibitor of both 5alphaR type I and II isoenzymes in prostate cells, but other cells showed no inhibition of 5alphaR activity following treatment with the plant extract. CONCLUSIONS: This investigation demonstrated the selectivity of the action of Permixon® for prostate cells. The morphological changes in the prostate are accompanied by an increase in the apoptotic index along with an inhibition in the activity of the nuclear membrane bound 5alphaR isoenzymes. No similar changes were observed in any of the other cells under investigation.

#6

hairlosshelp.com/forums/mess … erthread=y

anyone got an account on HLH? might be worthwhile giving this guy a PM and sending him this way