Dont wanna be a smartass but its type 1 not 2ā¦Fin inhibits Typ 1 very weak
Even the pure inhibiton of type 1 would let you loose Body hair. Sadly its not that simple. 
Brainbug, are you saying that the inhibition of allopregnanalone is not the main problem in your opinion?
No offense taken brainbug but I do believe itās a neurosteriod issue. Finasteride has been shown to significantly inhibit neurosteriods in the brain in addition Iām not sure itās just a type1 one conversion at play here. Read the study below.
If the root of the problem is a conversion of hormones to neurosteroids mainly allopregnanolone then supplementing more progesterone will not help. It almost seems like we need to kickstart the 5alpha reductase enzyme.
Are you saying if we get fucked up on vodka it cures us temporarily? What about your emotions?
It be a drug that helps us, until someone tries it we wont know.
One thing I am worried about is the extreme focus on the AR receptor theory in the studies conducted in Italy. If there is a problem with neurosteroids, shouldnāt this be emphasized? Dr. Traish and other doctors from what I understand are starting to focus on the neurosteroid aspect. Also, look at this:
medicalnewstoday.com/releases/52813.php
Could be that the DHT surge after quitting fin fried some of our brain neurons. Maybe this is what has resulted in messed up progesterone allopregnenalone conversion that has resulted in a cascade of side effects.
Is there really a DHT surge?? My DHt was still low 4 years after getting off of Prop.
Hey, np. We do have a big Problem with Neurosteroidsā¦ Some have brainfog, some dontā¦we do have big Problems, with our GABA A Rezeptors, we have big Problems, with Prostata, we have Problems with CARā¦ We have Problems with the gut, we have Problems with the thyroid gland, with our testicalsā¦ We have 100000 of Problems, but cureing the Gut or the Prostata will not cure the root.
We need to ask youself a few lil questions, Why do we loose Bodyhair? Why do our balls shrink? this has nothing to do with AP (ALLO). As you can see in this studie (Iknow it) 3a-HSD is also importantā¦5AR 1 and 2 also, why are they low for some people? Because they are expressed, by AREĀ“s Someone with very low ALLO, his dick will not shrink awayā¦he will have Brainfog and many other mental Problem but not a shrunken dick. Put some DHT cream on your dick and see what will happen. We respond negativ on androgensā¦ because of a negativ autoregulation, thats why nearly all AREĀ“s Produkts are down, or to muchā¦3a-HSDā¦5ARā¦and many many more. A very big question is, why does not everybody get it??? This as something to do with, how sensitiv the body was on androgens beforeā¦we all were very sensitv beforeā¦Haarlossā¦high libidoā¦and so onā¦The guys who gets later the sides, were not so sensitivā¦after a long time of DHT deprivation their bodys became more and more sensitivā¦until a point, weh the system brakes down.
A part of our cells stayed hypersensitiv, the parts, where mainly the 5AR2 is expressed jumped over the point and totaly shut down the expression. Thast why some haven even more hairloss than before or get acne or extreme oli skinā¦or some guys can gain up muscles or for other went the dick biggerā¦
Your post makes alot of sense except I know some people on this forum had very minimal hairlossā¦ Whats the solution? Try to turn on expression some how?
Thanks a lot, yes and for those people who had minimal hairloss before it gets worseā¦āmostlyā For those who had serve hairloss it stops. For other it changes nothing. this has something to do with our inividual epigenetik. This maks this Problem so complex. Turning just the expression of the 5AR2 for expample does nothingā¦just more DHTā¦and some men have a good DHT levelā¦ many here feel better, after raising androgen but that after a short time the cells downregulates the expressoin of the ARGĀ“s againā¦We have a Problem on the AR level and this leads to a Problem on the genexpression.
The Neurosteroids are only one part of the symptoms.
Brainbug- thatās not true. If you inhibit allopregnanalone you could be over producing progesterone which is known to down regulate the progesteone receptors having the actual affect of low progesterone, even though your levels are high. Low progesterone is estrogen dominance, which down regulates testosterone and many of the physical sides we are experiencing.
Estrogen dominance can also cause down regulated thyroid function (even with normal numbers) leading to loss of body hair, thinning scalp, eyebrows etc
Lifewasgood- I believe our bodies are cycling through so I have had times were getting drunk gave me great libido the next day and erection strength. I have also had moments were my nose/sinus clears up for a second and I get a random spontaneous erection. There is absolutely no doubt in my mind that Nuerosteroids are the key. Even read peopleās experiences, when they describe (as I do to) their head is clearer, they can breath clearly andā¦their sexual function improves as well
By the way, I have asked this many times. Can someone who claims they are entirely bald now, show me a picture or email me a picture?
I was thinking this also. Seratonin can have a similar effect on axon terminals: antidepressantsfacts.com/pinealstory3.htm
Also, worrying about if the researchers are on the right track is the last thing you should be worrying about.
How come? What if they are hyper focused on the AR theory and they miss something neurological? This happens in science all the time.
Not entirely bald, frontal recession