Testosterone metabolism and cyclosporin for 3 Adiol G upregulation for Rhumetoid arthritis patients

LINK:

rheumatology.oxfordjournals.org/ … /4/433.pdf

Great article…if you read the article and skim a few pages, you will see after a few months of treatment with cyclosporin, 3 Adiol G levels double.

Anonn1, nice find. A couple of things seen so far in the article:

1.) The normal range quoted for male Adiol-G is 20.1 +/- 4.5 nmol/L. While marginally lower than this recent reference:
propeciahelp.com/forum/viewtopic.php?t=2803
it still leaves any of us not supplementing T (or taking pituatary stimulants such as tamoxifen) abnormally low (and even many who are).

2.) The article discusses treatment with cyclosporin A causing hypertrichosis. Hypertrichosis is defined in this article
emedicine.medscape.com/article/1072987-overview
as
“Disorders of hypertrichosis are distinguished by the distribution of hair, as well as by the temporal pattern of growth, the possible associated congenital anomalies, and the possible inheritance pattern”

In this article, the sample size is much more significant(700+ individuals)

eje-online.org/cgi/reprint/145/1/1.pdf

Please look at either page 3 or 4…Look at the mean concentrations of 3 Adiol G. The mean concentrations is 30.3 n/mol.

:smiley: