Yeah this is the normal response.
Low T = high LH/FSH signals
this is primary hypogonadism
in us there is low everything
so it is more of a central process or due to unknown reasons
chronic fatigue patients exhibit same patern but with more effect on cortisol production
they have low ACTH and low cortisol
the funny thing is that in some exogenous small amounts of cortisol corrects their levels and also their ACTH RESPONSE normalizes. It is literally unexplainable contradictory to normal HPA feedback physiology.
But you have to consider that there is a role in the hypothalamus and before that as well, in the amygdala and other areas that may atrophy or malfunction during CFS.
CFS offcourse is another case of chronic (possibly infectious)-inflammatory condition so noone can determine exactly what is wrong and where. Enzymes play big roles there too, and some say that correcting enzyme speeds improves the outlook of the whole picture.
The most recent addition in the treatment is the use of macrolide antibiotics that speed up specific enzmyes catalyzing cellular immune reactions.
There is a anger from the CFS community against one famous doc who knew this for years but hid the information.