The following studies relate to treatments for anabolic steroid-induced HTPA shutdown and recovery.
Also, consider the fact that Finasteride is listed as a Testosterone analogue.
These documents may aid you with visits to doctors, to help you argue a case for boosting your post-Fin T levels.
Impotence related to anabolic steroid use in a body builder. Response to clomiphene citrate.
pubmedcentral.nih.gov/picren … obtype=pdf
Androgenic Anabolic Steroid Use and Severe Hypothalamic-Pituitary Dysfunction: a Case Study
thieme-connect.com/ejournals … 2003-39089
E. van Breda1, H. A. Keizer1, H. Kuipers1, B. H. R. Wolffenbuttel2
1 Department of Movement Sciences , Nutrition and Toxicology Research Institute Maastricht (NUTRIM), University, Maastricht, the Netherlands
2 Department of Endocrinology, University Hospital Maastricht, Maastricht, the Netherlands
The data of the present case demonstrate that the abuse of androgenic anabolic steroids (AAS) may lead to serious health effects. Although most clinical attention is usually directed towards peripheral side effects, the most serious central side effect, hypothalamic-pituitary-dysfunction, is often overlooked in severe cases.
Although this latter central side-effect usually recovers spontaneously when AAS intake is discontinued, the present case shows that spontaneous recovery does not always take place. We suggest that hypothalamic-pituitary dysfunction should always be considered in the differential diagnosis in athletes seen with typical presentation of anabolic steroid use.
In order to regain normal hypothalamic-pituitary function, supraphysiological doses of 200 μg LH-RH should be considered when the physiological challenge test with LH-RH (50 μg) fails to show an acceptable response.
Anabolic steroid induced hypogonadism treated with human chorionic gonadotropin
pmj.bmj.com/cgi/content/abstract/74/867/45
GV Gill
Endocrine Unit, Walton Hospital, Liverpool, UK.
A case is presented of a young competitive body-builder who abused anabolic steroid drugs and developed profound symptomatic hypogonadotrophic hypogonadism.
With the help of prescribed testosterone (Sustanon) he stopped taking anabolic drugs, and later stopped Sustanon also. [u]Hypogonadism returned, but was successfully treated with weekly injections of human chorionic gonadotropin for three months.
Testicular function remained normal thereafter on no treatment. The use of human chorionic gonadotropin should be considered in prolonged hypogonadotrophic hypogonadism due to anabolic steroid abuse. [/u]
Testicular responsiveness to human chorionic gonadotrophin during transient hypogonadotrophic hypogonadism induced by androgenic/anabolic steroids in power athletes.
ncbi.nlm.nih.gov/sites/entre … d_RVDocSum
Martikainen H, Alén M, Rahkila P, Vihko R.
Serum concentrations of testosterone, 17-hydroxyprogesterone, estradiol and several other unconjugated and sulphated steroids were analyzed before and after a single dose of hCG in 6 power athletes, who had used high doses of testosterone and anabolic steroids for 3 months.
The study was carried out 3 weeks after cessation of drug use, but the study subjects were still characterized by hypogonadotrophic hypogonadism.
The mean concentrations of serum LH and FSH were 2.6 +/- 0.3 and 1.1 +/- 0.03 mIU/ml (mean +/- SEM), respectively, and the concentrations of several precursors and metabolites of testosterone were lower than those before drug use.
In contrast, circulating concentrations of steroid sulphates were not decreased, with the exception of dehydroepiandrosterone sulphate.
After hCG injection serum testosterone and 5 alpha-dihydrotestosterone concentrations increased significantly, whereas no increases in estradiol and 17-hydroxyprogesterone concentrations were observed.
These results demonstrate that during transient hypogonadotrophism in adult men, the testicular responsiveness to a single injection of hCG is similar to that in prepubertal boys without any sign of steroidogenic lesion at the 17,20-desmolase step.
Therefore, the appearance of the possibly estradiol-mediated inhibition at the level of C21-steroid side-chain splitting in testosterone biosynthesis seems to be dependent on priming by gonadotrophins.
PMID: 3747510 [PubMed - indexed for MEDLINE]