SSRI to increase allopregenolone starting today

ncbi.nlm.nih.gov/pubmed/15677716 “Our results support the view that TP-induced aggressive behavior is the result of a TP-mediated neurosteroid biosynthesis down-regulation that can be reversed by the S-NFLX-induced increase of brain Allo content.”

Olanzapine and clozapine ncbi.nlm.nih.gov/pubmed/12496935

ncbi.nlm.nih.gov/pubmed/12420152 (dhea and SSRI)

ncbi.nlm.nih.gov/pubmed/14563706 (don’t understand)

ncbi.nlm.nih.gov/pubmed/12571361

ncbi.nlm.nih.gov/pubmed/12416991 (not done by 3alpha-HSD type III)

ncbi.nlm.nih.gov/pubmed/15069199

ncbi.nlm.nih.gov/pubmed/16996120 n(pregneg)

ncbi.nlm.nih.gov/pubmed/16432684

ncbi.nlm.nih.gov/pubmed/16249906

ncbi.nlm.nih.gov/pubmed/15677716 “Our results support the view that TP-induced aggressive behavior is the result of a TP-mediated neurosteroid biosynthesis down-regulation that can be reversed by the S-NFLX-induced increase of brain Allo content.”

ncbi.nlm.nih.gov/pubmed/15364024 (countering by finasteride)

ncbi.nlm.nih.gov/pubmed/15100702 (anti-psychotic drugs)

ncbi.nlm.nih.gov/pubmed/15069199 (see different isomers)

tab · May 25, 2018, 7:25am

Please update

jeffbrdr · May 25, 2018, 7:27am

I started taking a micro-dose of Prozac (fluoxetine) about 5 or 6 weeks ago, based on similar research I had seen. I take 2.5mg daily (normal dose is 20-40mg). So far, I’ve been happy with the results. My main issues were brain fog and anxiety. I have definitely noticed an improvement in both.

Many people on here stated that they felt ssri’s are a bad idea - most notably because of potential sexual dysfunction. 2.5mg has been shown to increase allopregnanolone significantly, but it’s not high enough to even touch serotonin. I haven’t noticed any sides, at all.

If you are experiencing brain fog symptoms several months after quitting, I would recommend trying low dose Prozac. I personally feel it can’t hurt anything, and in my case, I would say my mental issues have improved 50-75%.

visionquest99 · May 25, 2018, 7:27am

Not exactly on point but I found this info useful:

Increasing serotonin production leads to a reduction in dopamine production. This leads to a reduction in testosterone production. In most cases, the reduction would be mild since there are other factors controlling testosterone production.

5-HTP - which is 5-hydroxytryptophan, a derivative of the amino acid, tryptophan - is converted into serotonin (5-hydroxytryptamine) by the body. Almost all of this is used by the enteric nervous system (the gastrointestinal nervous system) - and is thus wasted. But some goes into the brain where it serves to increase serotonin levels.

Serotonin can inhibit sex drive and prevent orgasms.

But serotonin can in some people also increase sex drive.

Two common killers of sex drive are impaired thyroid function and impaired adrenal function - hypothyroidism and adrenal fatigue.

Serotonin is necessary to produce thyroid hormone. Thyroid hormone increases serotonin production.

Serotonin reduces the brain’s perception of stress. This reduces norepinephrine and ACTH production. This leads to a reduction of stress on the adrenal glands. This allows the adrenal glands to recover from stress and recover in function - thus recovering from adrenal fatigue.

Anxiety and depression can also reduce sex drive. Increasing serotonin can help reduce anxiety and depression, helping restore sex drive.

Mercked · September 7, 2018, 3:35am

Anyone want to update? It’s been almost a month since I took 1 mg Fin and two weeks after and onwards I’ve been experiencing sudden severe insomnia. Anyone have success with this shortly after withdrawing from fin?