There is an antibody for the 5 alpha reductase II enzyme used for research, I wonder if THAT is our problem, perhaps our bodies have reacted to the 5 alpha reductase enzyme with an anti-body. We may be immune to the effects of the 5AR enzyme, that would explain why my body releases them only for them to eventually be shut off.
I think that if our bodies are producing antibodies for the 5AR enzyme, the only way out of that is to just replace the DHT like I am doing, but there is an anti-antibody for this below
I have written enough about this topic but then gave up. I also sent emails to universities and labs and even called them to test antibodies in my blood but they told me there is no blood test in our labs. Universities did not reply my back. Maybe they think it is not possible. Please read my posts here viewtopic.php?f=27&t=5589&start=380&hilit=anti+bodies#p70433
I also suggested to exchange blood of two pfs patients of the same blood group, in the hope that may be our body will develop anti-antiDHT bodies. This looks far fetched idea but there are some chances that it is possible. I have discussed this idea with a fresh medical graduate. old drs on job with families they have one thing in mind, their fee and money they don’t want to waste their time.
Guys if any of you proceeds on this theory and contact labs, please let me know. just PM me with your plan and estimate and I will share the cost.
We have tried a lot of things with failure. Now give this theory a try.
Well, I emailed Dr Jacobs about this, so far he hasn’t replied to my emails since I paid him on Thursday, but he is a doctor and doctors are busy, so hopefully next week. I need to be patient, but it seems this maybe what is going on guys. It makes sense, it explains why my body releases 5AR enzymes and then all of a sudden they stop, my body must be producing antibodies for them.
If that is the case we are FUCKED, unless there is in fact an anti-antibody, that may be in the link above, but this goes beyond my expertise. However, since I have had success replacing DHT and have been able to restore my libido, sexual function and muscles with synthetic DHT, there is hope. The only problem is getting Estrogen under control which Dr Jacobs is an expert in and I am hoping he can help with that soon.
Also what ratios of testosterone to DHT are correct I have to figure out the optimum dose, but so far this is the best theory I have come up with. Since it has been postulated before, then the best theory we have come up with. It makes sense why this condition keeps coming back no matter what we do, our immune system is attacking the enzyme.
Again that synthetic 5AR 2 peptide may be the key, perhaps our bodies will see it as foreign and not attack it, or if our body does attack it, we can keep injecting more. Since some have recovered from this at least there is hope, and I will be experimenting with some different forms of DHT than Masteron to find the best one.
Be hopeful guys, with synthetic DHT I have full sexual function again, full sex drive, so long as estrogen is under control and that all depends on how much testosterone I inject, I now realize a lower dose is the best. My father has rheumatoid arthritis, that is a condition that is auto-immune, I wonder how many of you have that in your family, perhaps it makes us genetically predisposed to this.
I wonder if Embrel would help this disorder, my dad is on it, it suppresses the immune response, I may fucking try it and see what happens. Let’s see what Dr Jacobs says first whenever I hear back from him.
I am seriously thinking of trying Embrel, my dad is on it so I can access it quickly, I mean it is worth a shot, just to see what happens. I have absolutely no basis for it even working even if this is an auto immune disease, but we do know auto immune diseases are genetic. If embrel blocks rheumatoid arthritis in my dad, and it turns out this is an antibody to the 5AR enzyme, perhaps I will notice my 5AR enzymes turning back on. Even though I am using synthetic DHT, it does not block 5AR enzymes, and my skin isn’t producing much sebum like when my 5AR enzymes are on, when I produce 5AR enzymes I can see it on my face. It happens sometimes after an injection of any hormone then stops. I suppose it is worth a try huh?
You can detect the antibody by western blot and elisa methods. You just need to find a lab or a friend that works in a lab that is willing to test a regular citizens blood.
I emailed dr Jacobs, I’ll ask him about that, i think this direction is the most logical one, it’s extremely disappointing but logical. If I read correctly it seems there is an anti anti-5ar2 gene or something. I wonder if that could reverse this condition if this is the case. Can you imagine? Oh believe me, I’m not going quietly into the night, I’ll try everything, and anything dr Jacobs suggests, I know from my own experience this is treatable, it’s just difficult to control the estrogen, dr Jacobs is an expert on that so let’s see. My dick and sex drive are invincible on masteron though.
1-there are many autoimmune diseases which are not diagnosed easily
2-My friend has psoriasis for many years. His face, forehead, and hands are very badly affected. He has been on methotrexate for six years. Initially MT controlled it, at least did not let him get worse but now recently he is getting worse and he has begun to readjust his dose. But at least his life is manageable now.
It's starting to look like this is an auto immune condition, why else would it always come back and annihilate everything tried? The constant crashes and relapses sound like an immune system fighting something doesn't it? I wonder if embrel would do anything, it's a shot in the dark, but worth a try. Though some people have recovered and you don't recover from auto immune disorders, though this one is unique, what a nightmare
I’ll run that by dr Jacobs and I may sign up with dr Goldstein too, yea I’m spending a lot of money but I have seen this can be reversed. I just need some help, two doctors are better than one, what do you think?
Good advice, makes things easier anyway, I’m going to use what I know already and work with dr Jacobs, if I don’t get anywhere with him I plan to go down the entire list. I’m going to share all my experiences and protocols from them all with the forum
You know the only thing I can’t control is the estrogen dominance but I have reversed everything else, dr Jacobs is an expert in estrogen dominance it turns out. Maybe I can find the ultimate protocol from each doctor if not from dr Jacobs. No matter what happens masteron provides powerful sexual function and libido. That’s a major step, even during high estrohen surges. As well as muscle benifits. My experiences will help everyone here
Keep in mind, although you have controlled the situation, people do naturally recover without any hormones. So if it is autoimmune, how do some, like myself, slowly reverse and get clearly better
I hope it isn't autoimmune, Finatruth, it seems you started to recover after I suggested to eat asparagus and then you started eating a lot it, is that true? Even if you recover naturally you will get to a point that is functional but not optimal. Hormones are the way, but to each is own. We all have our paths, it's definitely promising that you are getting better.
I really find the auto immune theory to be extremely sound but extremely disappointing. It is hopefully some kind of damage that we recover from, but I don't want to be just normal, I want to be where I was before it hit. Hrt changed my life and made me into a stallion, I'm almost there again.
I think if some of us try different approaches it is not a bad thing, it could help researchers and perhaps give people options. I just am 34 and don't want to lose the rest of my 30s to this, I want to be a stud and stallion again, I'm close to it. I actually have been considering another round of hitting my body with high doses of PCT protocols to attempt to reactivate my 5ar. Knowing what I know now about estrogen could have made a big difference in the past when I was attempting to induce my own dht.
Also, it would be similar to what CDNuts did, I just am using powerful pharmaceutical grade hormones instead to get it done.
