Could this type of drug help allieve PFS? There are a few drugs under clinical trials…
en.wikipedia.org/wiki/Serotonin- … _inhibitor
SNDRI
A serotonin–norepinephrine–dopamine reuptake inhibitor (SNDRI), or triple reuptake inhibitor (TRI), is a drug that acts simultaneously as a reuptake inhibitor for the monoamine neurotransmitters, serotonin, norepinephrine (noradrenaline) and dopamine, by blocking the action of the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT), respectively. This, in turn, leads to increased extracellular concentrations of these neurotransmitters and, therefore, an increase in serotonergic, noradrenergic or adrenergic, and dopaminergic neurotransmission.
In clinical trials
DOV-102,677
DOV-21,947
DOV-216,303
Bicifadine
Tesofensine
RG7166
SEP-227162
Research compounds
Lilly LR-5182 WF-23
Naphthyl milnacipran analog[16] (also NMDA receptor antagonist)
3,3-disubstituted pyrrolidine[17]
Indatraline (Lu 19-005)
JZ-IV-10 (16e)
Methylnaphthidate (HDMP-28)
Naphyrone (O-2482)
D-161
3,4-disubstituted pyrrolidines[18]
Mazindol analogs[19]