did you ever think that maybe you just recovered the first time naturally despite all the things you were taking/trying? It’s completely possible so maybe you should take a step back and re-evaluate what has and hasn’t helped. You said before you were completely cured with the herbs when you obviously weren’t. The stuff your taking now, or for that matter trying again, is like 20x more potent than hydrocortisone.
Hi cytochrome,
thanks for the update. Your story is now clearer to me.
Can I ask if you had side effects during your finasteride therapy or did they appear upon quitting the drug.
5 years on fin seems quite a prolonged time.
Can you post your blood test before and during dexa intake - it seems you made some blood tests at the gynecologist?!
What was the rational to start the dex therapy in the beginning - dexa interferes with HPTA-axis.
Are you able to get in contact with the gynecologist again to ask him about it?
I guess many of us would be interested in the rational of such an approach.
Thanks again for coming back to the forum.
Take care
@ithappens
I am sure that I did not recover natural! And I am sure that Dexamethasone helped me to recover. 0,5mg is a very low dose with no side efffects. It supresses the adrenal system by 30-40%. There are many benefits I noticed by using Dexamethasone:
lost weight
less sweating
better mood
better sleep
no red eyes
In my theory DHEA is used to be converted into DHT and E2.
But a lack of 5ARII leads to estradiol domination.
Thats why Dexamethasone helps. Because it decreases E2 indircet by decreasing DHEA. I think that Androstendion is a adrenal hormon which interacts with cells in a different way to other androgens. So you cant compare adrenal androgens with gonadal androgens.
And I think that the androgen receptors in and on cells are getting more sensitive to androgens by decreasing adrenal androgens. But thats my own opinion. I am not sure.
Bloodresults before and after Dexamethasone:
Before Dexamethasone:
Testosterone: 7 (3-9)
Androstendion: 2.4 (1-4)
SHBG: 45 (10-70)
E2: 40 (10-40)
After Dexamethasone:
Testosterone: 6.5 (3-9)
Androstendion: 1.7 (1-4)
SHBG: 36 (10-70)
E2: 30 (10-40)
What can Dexamethasone do for my body, that would cause it to reform the proper function?
@scardinemd
I dont exactly know how it helped me. And I dont advice anything to anyone.
I will try this therapy with my body and if it works I will write it down on this forum. But this time I want to be 100% sure about the recovery!
Cytochrome. I can’t imagine how you must feel, having recovered and then taking finasteride again just to fall back in the hole. How long were you recovered for?
Despite what was brought forward in the last few posts; I’ll keep taking querectin anyway, in case it was what made you better.
Thanks for sharing your information. Your story of past recovery gives me hope.
Keep me posted with the dexa.
@Marquisd
Yes how silly. Taking this pill again. Okay. I made a topical solution and thought it would be safe. I was recovered from september 2006 till december 2006. Between the years I recognized Fin side effects again.
After all, there are two sides of view.
- How silly to take this dam drug again and falling again hell.
- I did recover! And what happend once will happen again! I promise!
when i do get an erection my Refractory period is much longer than normal
Uhh, thanks for sharing, but what does that have to do with this thread?
because the drug affected my refractory period like crazy and i want to know how it caused this and what i can do to fix this
Again, it has nothing to do with THIS thread.
oh i just posted it in this thread because there was the most action here and i would get the quickest reply
Typically you won’t get the reply you are looking for by hijacking someone’s thread. Especially since it has nothing to do with the topic of THIS thread. Start your own thread and if someone can answer you, they will. You would be better off doing some research on this site before asking questions that you could otherwise get the answer to with some reading.
I’ve just completed my first week on 1600mg Quercetin and 400mg Bromelain Enzyme. And I don’t feel any different so far. No sides from it or benefits.
I’m thinking It won’t change anything for the first few weeks, if it changes anything at all.
I’ll keep taking it and keep you guys posted.
I find the Quecertin(sp?) is causing a lot of Benign Muscular Fasciculation, it’s annoying. I have had it mildly since I was in my teens though.
your dates do not match your intial story.
Just finished my second week on quercetin. 1600mg a day
Don’t feel any changes yet, good or bad.
I’ll keep taking it and keep you guys posted.
Interesting thing. There’s a study in tissues showing that dexamethasone increases androgen metabolites level, through 5 alfa reductase activation. This may be the reason why this medicine has work for cytochrome. It’s a possibility.
endocrine-abstracts.org/ea/0 … 004p82.htm
Endocrine Abstracts (2002) 4 P82
INHIBITION OF DEXAMETHASONE MEDIATED ANDROGEN METABOLISM BY LEVAMISOLE IN ORAL PERIOSTEAL FIBROBLASTS
A Tilakaratne1 & M Soory2
1Periodontology, Faculty of Dental Sciences, University of Peradeniya, Sri-Lanka.; 2Periodontology, GKT, King’s Dental Hospital, London, UK.
Glucocorticoids modulate the effects of other hormones and also mediate cell function. Dexamethasone, in common with androgen metabolites, has been shown to increase alkaline phosphatase activity and bone specific marker proteins The aim of this investigation is to establish an androgen responsive element to dexamethasone as an index of regenerative potential in the periodontium, using the alkaline phosphatase inhibitor levamisole (L). 4 cell lines of oral periosteal fibroblasts were established in culture, using tissue isolated from periodontal patients (20-40y) requiring mucogingival surgery (obtained local Ethical Committee approval). Duplicate incubations of confluent monolayer cultures were performed in multiwell plates using 14C-testosterone or 14C-4-androstenedione as substrates in Eagle’s MEM. Optimal concentrations of dexamethasone (1 and 3 micrograms/ml) were added to the incubation in the presence or absence of an inhibitory concentration of L(30microgram/ml). At the end of a 24h incubation period, the medium was solvent extracted with ethyl acetate, evaporated to dryness, solubilised in chloroform and subjected to thin layer chromatography for separation of metabolites. The separated metabolites were quantified using a radioisotope scanner. Dexamethasone caused significant stimulation of 5 alpha reductase and 17beta hydroxysteroid dehydrogenase enzyme activity, increasing the yields of DHT by 44-48% and 4-androstenedione by 35% from testosterone as substrate. L inhibited these enzyme activities by 28-30% and there was an intermediate response, with values similar to those of controls, when Dex was combined with L (n=6; p<0.01). When 4-androstenedione was used as substrate, the metabolites formed were DHT, testosterone, diols and androstanedione. Except T, other metabolites showed significant increases of 26-45% in response to Dex, 23-31% inhibition by L and intermediate responses similar to control values in response to combinations of Dex+L. All values were significant (n=6; p<0.01). Androstanedione is an important intermediary in the formation of DHT from androstenedione, by 5 alpha reduction. The result indicates that the anabolic potential of dexamethasone in stimulating biologically active androgens can be mediated by alkaline phosphatase activity.
Very important information! Thank you!
I remember another important thing!
At the time I took Dexamethasone I used a med called mutaflor. This seems to be a mediator for the metabolic effect of Dexa. See ur posted study. That could mean that e.coli forsters the effect of dexamethasone on activation the reductase encym…
see: en.wikipedia.org/wiki/Alkaline_phosphatase
onto something here…
Again, let a doctor prescribe this…You must be under supervision, this is a powerful drug…20x more power than hydrocortisone.