SCFA Production and epigenetic regulation of gene expression

I look at possibilities. This is a pretty good quick summary of that.
Maybe I would call this a drug induced disruption of an ecosystem, maybe not so specific to the drug itself.
You can find pretty good evidence of this possibility in Accutane and SSRIs.

Gut Microbiota and Salivary Diagnostics: The Mouth Is Salivating to Tell Us Something

Symbiotic Host–Flora Relationship: Examples of Important Roles That Gut Microbes Play in Functions Essential to Human Health and Survival

Function Effect
Chemical transformation and metabolism of xenobiotics Eliminate or transform environmental chemicals in the air we breathe, extraneous food additives, pharmaceuticals
Immune system Induction, basic development, training and function
Production of SCFAs Inhibit inflammation; influence multiple regulatory pathways (thereby affecting epigenetic regulation of gene expression)

Of the different ecosystems of flora that inhabit the human body, the gut microbiota system is emerging as the preeminent “microbial organ” of study, and there is great expectation that by better understanding the complexity of the role of microbiota, our microbiome will become an indispensable and integral part of our personalized healthcare in preventing and/or treating diseases more effectively and in a more precise and targeted clinical approach.3,14–19 Indeed, gaining a better understanding of the gut microbiota system may help to enable a revolution in precision medicine20,21 across a wide range of diagnostic, preventive, and therapeutic approaches.15,17