Many wonder how Saw Palmetto and Rutin-Quercetine do to be worse than Finasteride since they are natural substances. Guys, this shit not only suppresses the 5α-Reductase enzyme and stands out as an antiandrogen, but it also suppresses the signal IGF-1 (insulin-like growth factor-1) or somatomedin, which is fucking incredible that not even finasteride inhibits.
IGF-1 appears to have a direct connection to the AR receptor.
Here is perhaps the reason why, this plant and flavonoid can be much worse of finasteride.