Review article on actions of propecia
jcasonline.com/article.asp?issn=0974-2077;year=2009;volume=2;issue=1;spage=12;epage=16;aulast=Anitha
Review article on actions of propecia
jcasonline.com/article.asp?issn=0974-2077;year=2009;volume=2;issue=1;spage=12;epage=16;aulast=Anitha
this article is in favor of finasteride
Conclusion
Although a relationship has been established between finasteride and sexual dysfunction in the literature, the analysis of the role of androgens in male sexual function and the evidences from large population-based long-term placebo-controlled studies using validated questionnaire and objective method for assessing sexual function suggested no substantial evidence of ED in men receiving finasteride. Low ejaculatory volume is the only causal relationship between finasteride and sexual dysfunction. Finasteride has been an effective drug in preventing low-grade prostate cancer but its role in increased incidence of high-grade prostate cancer has been attributed to better performance of PSA screening in prostate cancer detection. The effects of both doses of finasteride (5mg and 1mg/day) on prostate and PSA levels are almost similar. So, as dermatologists, we should be aware of the potential risks and benefits while treating baldness in young men with long-term finasteride.
dermatologist stuff
This line was interesting –
“The administration of finasteride 5mg/day for the treatment of BPH results in 60-93% reduction in circulating DHT levels from the baseline.”
I know they’re talking about 5mg and not 1mg but I not sure it makes much difference. I wonder if those of us who are really hammered by this ,ie extreme overnight penile shrinkage, were closer to the 93% reduction and now have super over expressed AR gene.