Retinoids are essential in the development and function of several organ systems; however, deregulated retinoid signaling can contribute to serious diseases.
Quite a bit here. I think its worth saving. Again I dont think it would be lack of vitamin A intake, but how it gets utilized (or doesnt) after that.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447240/#:~:text=All-trans%20retinoic%20acid%20(RA,cancer%2C%20neuroblastoma%2C%20and%20glioblastoma.
I will post this quote again, I cant even remember where I pulled this from but still, maybe this could be why there could be upregulation of the AR gene if true.
"Surprisingly, androgens can partially compensate for the loss of RA signaling, and we identify a link between the endocrine system and RA signaling"