Again, there could be a buried connection here of what finasteride is capable of altering.
These data provide the first description of a prostate-specific gene where androgen plays a minor role in transcriptional regulation, raising the question of whether the classical transcriptional role of androgen–AR is sufficient as a mechanism to achieve prostate-specific expression. It also shows that RA might play an important role not only in prostate development but also in its function as a matured organ. Controlling the expression of prostatic genes and antagonizing the effects of androgen is important and perhaps necessary to control prostate gland homeostasis.