Taking Accutane maybe could halt this process (natural retinoic acid generation), maybe in some long term.
Here they are talking about excess retinal being toxic to vision. Im not sure if the same thoughts could be applied systemically.
All- trans -retinoic acid generation is an antidotal clearance pathway for all- trans -retinal in the retina*
the generation of atRA may significantly relieve the cytotoxicity of atRal in human retinal pigment epithelial (RPE) cells.
Free atRal released from rhodopsin following photoexcitation functions as an indispensable intermediate of the visual cycle (Liu et al., 2016). These molecules are cytotoxic and could cause retinal degeneration when excessively accumulated in the retina (Maeda A et al., 2008; Maeda T et al., 2009; Li et al., 2015). Thus, effective clearance of atRal is crucial for retinal health and vision maintenance.