This might be a pretty good read here.
Retinoic acid may be more important in males than females and if a person wanted to say the androgen receptors are overexpressed, this could further suppress retinoic acid function.
Retinoic acid exerts sexually dimorphic effects over muscle energy metabolism and function
RA induces proliferation of cultured myoblasts and sustains their survival, suggesting a contribution to skeletal muscle regeneration (30, 31). Pharmacological dosing with RARγ agonists stimulates skeletal muscle repair and reduces extent of fatty fibrotic tissue lesions in a muscle injury model (32).
The present data complement insight into the anti-obesity effects of RA by revealing that endogenous RA promotes skeletal muscle fatty acid oxidation, glucose uptake, mitochondrial function and ATP biosynthesis in males, but restricts the same in females.
In contrast to estrogen actions, androgens repress RAR mRNA in rat prostate (59), whereas RA suppresses androgen receptor expression in rat testis (60). The decreased performance by Rdh10 +/− males would reflect decreased RA signaling and amplified repression of RAR by androgen.