Hello,
I would like to know if the effects of propecia 1mg and 5mg are the same in the PSA value reduction - also what is the percentage reduction from original value, for 1 mg ?
Another question would be, what is the PSA value recovery rate after cessation of the treatment? what should i expect after 12 months of no use ?
Thanks!
Yes, both Propecia 1mg and Proscar 5mg have near identical effects on PSA just as they do on serum levels of DHT, due to near flat dose response rate of drug (Finasteride).
~ 50%
Should start going back to normal within 3-6 months, according to (graph)
pdf.medrang.co.kr/Kju/040/Kju040-11-18.pdf
PROPECIA
cortlandtforum.com/Finasteri … le/114703/
As little as 1 mg/day of finasteride can seriously distort the results of prostate-specific antigen (PSA) screening, a study shows.
That’s the dose of the drug Propecia used by more than 4 million men to treat male-pattern baldness and associated in the study with lowering serum PSA concentrations by as much as half. Finasteride is also sold as Proscar for BPH, but Proscar was not tested in this study.
When physicians are assessing whether patients taking Propecia require prostate biopsy, “the PSA level needs to be multiplied by two,” the study group concluded, in order to compensate for the artificially lower PSA levels.
Researchers compared the effect of finasteride 1 mg/day and placebo on PSA levels in 355 men for 48 weeks. Among those taking finasteride, men in their 40s showed a 40% median decrease in serum PSA at study’s end. Those aged 50-60 years showed a 50% decline.
Placebo recipients in their 40s had no change in serum PSA levels, whereas those aged 50-60 years had a median 13% increase. The increase in the older group was expected because PSA levels rise with BPH, and the risk of BPH increases with age.
The study was funded by Merck, which makes both Proscar and Propecia.
Bottom line:
Clinicians should routinely ask about Propecia use when taking a prescreening history for PSA testing, said lead investigator Anthony V. D’Amico, MD, PhD, an oncologist at the Dana-Farber Cancer Institute in Boston.
PROSCAR
Thanks!
Do you know if the experiment(in the korean article) was conducted using 1mg or 5mg?
cheers,
It doesn’t say, but like I said in my post above, it doesn’t matter anyway since Finasteride has almost the same effect on PSA and DHT at 1mg or 5mg.