I plan to post a lot of what I have learned about prostatitis later, but for the moment Ill just say that one should NOT get obsessed with chasing hypothetical pathogens in the prostate in the absence of proof (although the theory that some intraprostatic pathogens are impossible to culture makes a lot of sense and may be true in many cases). Especially since antibiotherapy can introduces many adverse effects (the lesser one being gut dysbiosis which is still a huge problem) and even worsen the prostatitis.
“Prostatitis”/CPPS may in some cases be in fact due to SIBO or other gut “infections” (ill post a study about that later), also be in fact due to a muscular problem in the pelvic floor (check the stanford studies, pelvicpainhelp.com), and even be fungal in nature (intra-prostatic candida or cryptococcus, ill post studies about that later too). In all these cases antibiotherapy wont be of any help and will most likely WORSEN the problem in the long term. In the case of proven intraprostatic bacterial infection, antibiotherapy with daily prostatic massages is still probably the best therapy.
The fact is that the etiologies and possible treatments of prostatitis/CPPS are still very much a mystery to medecine.
Although imperfect, the best diagnostic tools to date are still the DRE + the 4 glass stamey test (or a simplified version)+ a transrectal ultrasound with color doppler (not many radiologists are competent in using this tool for diagnosing prostatitis though, so you have to look for ones with experience in prostattiis -beleive me)
If the 4 glass test reveals increased leucocytes in the post-prostatic massage urine but no bacteria, you can try some antibiotics if you really want to, but NO QUINOLONE. You can also try antifungals as some ppl have found success with them (and not only on this forum). The theory that prostatitis may be autoimmune makes a lot of sense too. You can try NORMAST, maybe LDN, and other dietary etc approches in this case.
If a bacteria (or fungus) is successfully cultured, use an antibiogram/antifongigram to select the appropriate abx/antifungal.
If no leucocytes are found, and if the TRUS shows a “clean” prostate, FORGET ABOUT PURSUING THE TYPICAL PROLONGED ANTIBIOTHERAPY. Explore the gut inflammation etiology or pelvic floor dysfunction.
I will post a lot of relevant and useful scientific links later.
Phytotherapy with antiseptic herbs (the UTI ones) is worth exploring too. Crenotherapy as well.
But DO NOT let your urologists prescribe you abx without having done any of the previous tests.
Thanks for your attention.