Propecia 10 years ago for 2 weeks, DHT out of range

Hi guys I’m 32 years old guy from Italy I have PSSD after adverse reactions of citalopram last december I don’t have any sexual problem before, today I have reduced strength of the erection and delayed ejaculation mainly.
But 10 years ago in 2004, I took finasteride for about 2 weeks together has a lotion with minoxil with topical antiandrogen, after two weeks, I stopped because I realized that would not work for hair and I realized that it was potentially really dangerous.
Since I have never had sexual problems before the adverse reaction to citalopram last December I took only 7 drops and after I stopped now I’m 9 months drug free.
Today I have withdrawn my blood test, I wanted to control the DHT because I thought that 10 years ago I took finasteride for two weeks, this is the result:

LH: 5,19 mUl/ml normal range 1,70 – 8,60 eclia

Estradiol 25,37 pg/ml normal range 7,63 – 42,6 eclia

Prolactin 353,8 pUl/ml normale range 86,00 – 324,00 eclia

TESTESTORENE 6,01 ng/ml normal range 2,50 – 8,36 eclia

Free Testosterone 20,8 pg/mal normal range 8,70 – 54,70 RIA

DHT diidrotestosterone 2.050 pg/ml noramal range 250,0 – 990,0 ELISA

TSH 4,02 pUl normal range 0,27 – 4,20 eclia

Cortisol 16,6 pg/dl normale range 4,5 – 22,7 CLIA

Today I call my endocrinologist I’m really afraid of the results of DHT, any advice?

I wanted to try Dostinex / Cabergoline to lower my prolactin and treat my PSSD, but it seems that Dostinex can raise the levels of DHT.
My endocrinologist told me not to worry about taking propecia for two weeks 10 years ago, that if I had not had any problems then, now probably my problems were due to adverse reaction to citalopram in December, Instead it seems that even the propecia 10 years ago did damage, only that it was silent, I have never taken anything belonging propecia for two weeks 10 years ago that could have messed up my DHT levels .
Monday will see the endocrinologist, I’ll see what he says.

I add my story with my symptom here.

Welcome to our community. Please fill in the following template as a way of introducing yourself, and helping others to understand your background and situation.

Where are you from (country)? Italy

How did you find this forum (Google search – if so, what search terms? Via link from a forum or website – if so, what page? Other?) Google Search

What is your current age, height, weight? 39…174 cm, 67 kg

What specific drug did you use (finasteride, dutasteride, saw palmetto, isotretinoin/Accutane, fluoxetine, sertraline, citalopram, leuprorelin, etc…)? Finasteride for 2 weeks around 15 years ago, adverse reaction to 7 drops of Citalopram (single dose) 7 years ago

What dose did you take (eg. 1 mg/day, 1 mg every other day etc.)? 7 drops

What condition was being treated with the drug? hair loss finasteride, depression Citalopram

For how long did you take the drug (weeks/months/years)? finasteride around 2 weeks, Citalopram only one time (single dose)

How old were you, and WHEN (date) did you start the drug? 22 years finasteride, 33 years Citalopram

How old were you when you quit, and WHEN (date) did you quit? 22 finasteride, 33 citalopram

How did you quit (cold turkey or taper off)? Cold turkey

How long into your usage did you notice the onset of side effects? Immediately with Citalopram

What side effects did you experience that have yet to resolve since discontinuation? ED, emotional numbness

Check the boxes that apply. You can save your post first, then interactively check/uncheck the boxes by clicking on them. If your symptoms change, please update your list.

Sexual
[ ] Loss of Libido / Sex Drive
[ x] Erectile Dysfunction
[ ] Complete Impotence
[ x] Loss of Morning Erections
[ x] Loss of Spontaneous Erections
[ x] Loss of Nocturnal Erections
[ ] Watery Ejaculate
[ ] Reduced Ejaculate
[ x] Inability or Difficulty to Ejaculate / Orgasm
[ ] Reduced Sperm Count / Motility

Mental
[ x] Emotional Blunting / Emotionally Flat
[ ] Difficulty Focusing / Concentrating
[ ] Confusion
[ ] Memory Loss / Forgetfulness
[ ] Stumbling over Words / Losing Train of Thought
[ ] Slurring of Speech
[ ] Lack of Motivation / Feeling Passive / Complacency
[x ] Extreme Anxiety / Panic Attacks
[ x] Severe Depression / Melancholy
[ ] Suicidal Thoughts

Physical
[ ] Penile Tissue Changes (narrowing, shrinkage, wrinkled)
[ ] Penis curvature / rotation on axis
[ ] Testicular Pain
[ ] Testicular Shrinkage / Loss of Fullness
[x ] Genital numbness / sensitivity decrease
[ ] Weight Gain
[ ] Gynecomastia (male breasts)
[ ] Muscle Wastage
[ ] Muscle Weakness
[ ] Joint Pain
[x ] Dry / Dark Circles under eyes

Misc
[ ] Prostate pain
[ ] Persistent Fatigue / Exhaustion
[ x] Stomach Pains / Digestion Problems
[ x] Constipation / “Poo Pellets” (alternate with diarrhea)
[ x] Vision - Acuity Decrease / Blurriness
[ ] Tinnitus (ringing or high pitched sound in ears)
[ ] Hearing loss
[ ] Increased hair loss
[ ] Frequent urination
[ ] Lowered body temperature

[ ] Other (please explain)

What (if any) treatments have you undertaken to recover from your side effects since discontinuation of the drug? HCG Injections, Cabergoline, Cialis Daily 5 mg for 2 month, Proviron

If you have pre or post-drug blood tests, what hormonal changes have you encountered since discontinuing the drug (please post your test results in the “Blood Tests” section and link to them in your post)?

Anything not listed in the above questions you’d like to share about your experience?

Tell us your story, in your own words, about your usage and side effects experienced while on/off the drug.

I wrote this post despite having been a member of the board for 7 years, because I hadn’t done it before. The first two years of PSSD were pretty good for me, I was a bodybuilder I weighed 80kg for 1.74 cm height. Then I developed third degree hemorrhoids which forced me to stop weight training, and currently weighing 67kg, the hemorrhoids came after taking a neurologist-prescribed supplement with tryptophan and magnesium for nine days. Prescribed by an idiotic neurologist one month after the adverse reaction to Citalopram, when I saw it increased serotonin levels I threw it in the trash. However for two years I could continue to train and I was quite well, some days I forgot about PSSD. After developing third degree hemorrhoids I had to stop training. I took various medications to try to treat PSSD prescribed to me by an endocrinologist and urologist a few years ago They who believe in PSSD / PFS. Low dose HCG for one month, Cabargoline for high prolactin levels 0.5mg three times a week. I was relatively well overall, I work in the healthcare sector, even if it is difficult for me to continue working now, until two months ago. Two months ago during an eye examination to change the gradation of the glasses, the old ophthalmologist used drops of local anesthetic called Benoxinate (Oxybuprocaine) which now I know can block ion channels in a similar way to Citalopram. Dr David Healy speculates this as one of the causes of PSSD. After this drops I developed a pathology called central serous chorioretinopathy, now I am followed by a competent ophthalmologist who however says that I had this problem since before the drops. I also have neurological symptoms like hand and feet pins and needles and hot flashes, which I hope to resolve. Unfortunately we are sensitive to any drug, and any drug can cause us big problems, even a banal anesthetics. I have been a member of the board for a long time and today I wanted to share my story.

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Thank you for sharing @Luke83

Thursday I have to do the new blood tests, I hope the DHT is lowered, the other time it was lower, the prolactin was always a little higher. If it’s still high I think I’ll have to go back to my endocrinologist and do another cicle of Dostinex. My hyperprolactinemia appears to be induced by previous SSRI use.

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I started training a bit with weights again, my ophthalmologist said I can do it. I went from 67 to 68 kg in a week, I increased my caloric intake a little, I am training lightly. For now things are going well, I just feel a little tension in my head, maybe it is the effect of the eye drops that the old ophthalmologist used two months ago that he still has to be disposed of completely.

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I did new blood tests, and now the values all seem perfectly normal.

Prolactin 147 Ui/ml 45 - 375 CLIA
Progesterone 0.4 ng/ml 0,2-1.2
Testosterone 21,7 nmol/L 5,6 - 26.0
Free Testosterone 14,20 pg/ml 1,00 - 28,28
DHT 540.5 UI/ML 250,00-990,0
Cortisol 24,5 ng/dl 9,5 - 22,4

Only cortisol seem little high, and is related to the eye problem. This shows that PSSD/PFS is a problem of overexpressed receptors and not of hormonal values.

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I am very happy to see your numbers are so much more normal. Did you do anything to lower your DHT, or did it drop naturally?

2 Likes

Thanks New Yorker.

I did not take anything to lower the DHT, luckily it had already lowered in the past. But I had problems with high prolactin, in the past I have taken medications prescribed by my Endocrinologist, HCG injections for a month and dostinex.