Prolactin levels before & after dopamine agonist treatment

Prolactin levels before and after dopamine agonist treatment.

Note the grey shaded area, which is considered the normal (optimum) range for men.

More info: pituitary.mgh.harvard.edu/NCBV9I1.htm

"Figure 2. Serum PRL levels at baseline and after dopamine agonist administration in men with microprolactinomas and macroprolactinomas. PRL levels are displayed as loge values.

The shaded area represents the normal range for serum PRL levels (<15 ng/mL). Reprinted from the Journal of Clinical Endocrinology and Metabolism with permission from the Endocrine Society (1)."

What does this mean? Something about prolactin levels out of range being harmful, and/or something pertaining to Finasteride??

Read the link…

“High prolactin may decrease pulsatile GnRH secretion by the hypothalamus, leading to a decrease in pituitary gonadotropin secretion and subsequent testicular dysfunction. This hypogonadotropic hypogonadism will result in low testosterone levels. Testosterone deficiency in men is associated with a number of complaints related to sexual dysfunction.”

From what I understand, levels associated with Prolactinomas are generally found to be MUCH higher than the reference range (ie, often in the 30-100s, in the 100s, or 1000s). Regardless, a guy approaching the upper end of the reference range (ie, 13 in a range of 1-15 for Prolactin) or above it may want to discuss an MRI scan or possible dopamine agonist treatment options to lower prolactin. I recall reading somewhere that Dr. Shippen likes to keep prolactin between 3-5, but I could be wrong.

Besides being caused by a prolactinoma, Prolactin can also be increased due to elevated estrogens (common in ex-Fin users) and due to Hypothyroidism (also a problem some guys have post-Fin) –

cnn.com/HEALTH/library/DS/00532.html
“Excess production of prolactin may occur in people with hypothyroidism — insufficient hormone production by your thyroid gland. This usually occurs only in people with longstanding untreated hypothyroidism.”

Did it say in that study mentioning Clomid as a cure for 20% of men with gynecomastia that Clomid also decreases Estrogen??
Do you remember which study I am referring to?
I am getting ready to try Clomid, as soon as I get my new health insurance and round of bloodtests.
I know this is little unrelated… except for the mention of estrogen…

is also L-Dopa supplement doing the same effect as Dopaminergic agonist to lower prolactin?

I would like to say ppl using drugs to low prolactine to be carefull about the long term cause I took it just for 2 weeks did the blood test after quitting by 2 weeks and I have prolactine at 3,8 (3-20)…so it can slow it very fast at least in my case .