Progesterone Inhibits basal and gonadotropin-releasing hormo

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#1

I appologize if this study has been previsouly posted. As many of you know, I am the leading proponent that finasteride has altered the progesterone to Estrogen ratio in our brains, causing a cascading effect and symptomolgy. My theory is that all of us anxious people had low levels of progesterone, which were depleted with finasteride use or cesation of use. I would actually be curious to know if those that are most anxious expereince the “worst” or most “devastating” side effects, but I digress. I am now hearing rumblings that they may have isolated the problem with regards to gene expression. This fits so snuggly and soundly into my theory, like a glove. In any event, hang in there everyone, I feel like something is going to break for all of us very soon.

Progesterone Inhibits basal and gonadotropin-releasing hormone induction of luteinizing hormone beta-subunit gene expression

ncbi.nlm.nih.gov/pubmed/19106225

#2

Amen. I like the optimism brotha :slight_smile:

#3

Do tell.

#4

Do you say that the pfs foundation found the cause of pfs?

#5

I like the optimism. You give us hope.

#6

Hi Finatruth,

Assuming your theory is correct can you explain how PFS has caused my urine to get very dark ?

Also are you saying that if we add Progesterone to our bodies everything will go back to normal ?

#7

Lets see what the next study entails and what is going to be discussed/released at the neurosteroid convention before we jump to saying that “they have found the cause”

Mark, this is my opinion. Unfortunately I don’t believe it’s as simple as that for various reasons. Some of which are 1) is the receptor site downregulated, 2) is it an imbalance, 3) how much is needed, 3) and maybe the most important, what is the delivery method. Every major study that I have seen using progesterone to demolish the protective effects of progesterone is done intranasaly or intravenously

#8

Hi Finatruth,

Just another question,

Is your theory able to explain how many of us dont get colds of flu anymore ?

#9

buddy have you done liver tests? are your liver enzymes ok? dark urine some times indicate hepatitis. I have very frequent urination but my urine is clear as glass. My enzymes were below normal range now are normal range as opposed to elevated elevated.

#10

I’ve been using Progesterone for the last 4 days and have not noticed any improvements yet.