Annurca Apple Polyphenols Have Potent Demethylating Activity and Can Reactivate Silenced Tumor Suppressor Genes in Colorectal Cancer Cells
Has anyone tried Demethylating with Annurca apple extract its available on Amazon etc. Would this work on non cancerous cells?
https://academic.oup.com/jn/article/137/12/2622/4670012
We observed a significant reduction in expression of DNMT proteins after treatment without changes in messenger RNA. In conclusion, APE have potent demethylating activity through the inhibition of DNMT proteins.