Hello guys, since I have been here I have started Hydrocortisone therapy (low dose), by the third day on it, my muscles had regained their full pump and hardness and normal response to testosterone like before PFS. My dick increased in size ALOT, I guess I forgot that it was much bigger before, 9 months is a long time. ALL sexual side effects vanished (please note I am on pramipexole 0.20mg along with Vitex 1600mg a day, wellbutrin 300mgXL(been on for years, long before PFS), Testosterone Enanthate 200mg a week). I am on Masteron Enanthate, but only for cosmetic reasons to control water retention, otherwise I wouldn’t need it, in fact I found it to be counter productive in more than a very low dose.
It seems all these crashes we have experienced are Cortisol crashes, I thought they were estrogen crashes, but estrogen requires a lot of cortisol. After constant bombardment with messed up hormones, our adrenals give in, if you check adrenal fatigue forums, you will find their symptoms mirror PFS. The problem with this forum is most of the guys here are in the UK or other countries that do not have hormone replacement (including Cortisol replacement) so you guys fear what you do not understand. I had someone here warn me of the dangerous of these drugs. Further inspection found that the doses used to treat Adrenal fatigue are so low, that they are not considered to be in any way dangerous by adrenal fatigue doctors.
5MG of Prednisone is equal to 100mg of hydrocortisone, for adrenal fatigue, the doses range around 5mg of hydrocortisone at a time, 3-4X a day (those are my doses which my Adrenal fatigue doctor says are so low they are almost homeopathic). He wanted me to go on something like 15mg when I wake up and 5mg in the afternoon and 2.5mg later. Moonman wrote up a very good thread about this that I will enclose here, he used 7.5/7.5/5/5, I highly recommend his dosing, worked best for me, I lowered it due to some bloating in my face, I am too vain.
Cortisol seems to be the final issue here, I had 100% reversal on this, in fact, on pramipexole, at 0.20mg, whenever cortisol kicked in I got so horny that I couldn’t focus on anything. I actually had to lower the dose as my libido got so crazy, like beyond crazy, I enjoyed it for a week or so, but my dick got sore after jerking off about 7X a day (no joke).
I noticed all the PFS docs address testosterone, but none of them (except Dr Bailey) address Cortisol, Cortisol is required to respond to testosterone. This now I can see is why guys have responded to test and then stopped, they had some cortisol to respond, finally exhausted their supply and suffered a cortisol crash. All along from day one cortisol has been the main culprit, the reason AI’s helped is because they lowered estrogen which exhausts cortisol. So less estrogen, more cortisol to respond to testosterone, I had not expected a response to hydrocortisone like I had.
Now, moonman never fixed his libido, there are a few guys here (very very few) who have another issue going on with their libido, but I have yet to see any of them titrate up on Pramipexole all the way to 1MG starting out at 0.125mg and titrating slowly every week. That being said, this is really bad if you live in the UK or europe as there simply is no medical help for Adrenal Fatigue and seemingly none for hormone replacement therapy. Cortisol is the fuel to all the hormones, and as I started it, 5AR activity increased A LOT, mood went back to pre PFS, everything did, I couldn’t believe this one hormone could do so much.
So that is the missing link with intermittent response to testosterone it seems. Someone here, someone well known, an active poster is following me step by step, he is improving as expected step by step. He has promised to post when he is at recovery point, if everyone here fixed testosterone and adrenal fatigue, this forum would be empty. Trying to fix it naturally simply won’t cut it, and the irony is many of the “natural” things you guys are doing are stressing your adrenal glands and making the situation worse.
Moonman told me PFS sufferers first have very high cortisol which then drops down to low cortisol. I had finally experienced a total cortisol crash where it got low and thus fatigue, the symptoms of high and low cortisol are very similar. That can be confusing, but you can order 24 hour cortisol urine tests online. I didn’t want to go down this road for a long time, mostly out of the fact that I was not that well versed in this area of hormones at all, so I can understand your fears of the unknown. I suggest you guys read about Adrenal Fatigue, go to the forums, they suffer crashes, they have many of the same symptoms. I believe this is what lingers on for years, everything else heals except testosterone and cortisol, the good news is you only have to be on hydrocortisone for about 1 year, as your adrenals heal you taper off.
So there is a cure for adrenal fatigue, that is nice huh? I am 9 months in and at about 90% and stable for a while now. I also noticed on hydrocortisone my dick is bigger when flaccid as well, a lot of things just improved to 100%
Check out Moonman’s post