I took Propecia for 1 year, then Avodart from 2005 to 2011.
I have persistent sides, but I’m going to the doctor next week. The GP will hopefully send me to a good specialist. I thought that maybe low T was the cause of my weak erections and belly fat, but this is terrifying:
ncbi.nlm.nih.gov/pubmed/24823464
“5α-reductase type 1 modulates insulin sensitivity in men.”
Our objective was to test the hypothesis that inhibition of 5αR1 causes metabolic dysfunction in humans.
CONCLUSION:
Dual inhibition of 5αRs, but not inhibition of 5αR2 alone, modulates insulin sensitivity in human peripheral tissues rather than liver. This may have important implications for patients prescribed dutasteride for prostatic disease.
I don’t know what to do. It leads to fatty liver, forget about an oversized belly.
But then there’s this:
ncbi.nlm.nih.gov/pubmed/24344872
“Testosterone with dutasteride, but not anastrazole, improves insulin sensitivity in young obese men: a randomized controlled trial.”
Abstract
INTRODUCTION:
Testosterone (T) administration to men increases T, estradiol (E2), dihydrotestosterone (DHT), and fat-free mass (FFM), and decreases fat mass (FM) but does not consistently improve insulin sensitivity (IS).
AIM:
The aim of this study was to examine the effects of T administration in obese, nondiabetic men on body composition and IS, and to determine if inhibition (i) of metabolism of T to E2 with anastrazole or to DHT with dutasteride alters these effects.
CONCLUSIONS:
The combination of T plus dutasteride improved body composition and IS while T alone improved body composition but not IS, suggesting that when T is administered to men, reduction to DHT attenuates the beneficial effects of aromatization to E2 on IS but not body composition.
Does anyone have any insight into what I should do? Tell my doctor, sure, but they often don’t grasp everything. I’m certainly not going to take Dutasteride and some random T, but I’m terrified about what I should do going forward. Thanks for any help you can provide.