While that makes intuitive sense, it is too simplistic. There is evidence that suggest a u-shape curve, where at certain points along the curve under- and overexpression result in similar disease states (broadly speaking).
AR overexpression in PFS patient tissue has been confirmed by two studies. Plus, we are collaborating with a leading AR expert (in connection with refractory prostate cancer) and a researcher who has identified a new form of androgen insensitivity, who both find it likely that AR overexpression is key to understanding this condition. Save to say, they understand androgen signaling and the role of the AR.
Please see here for a very detailed overview: https://www.propeciahelp.com/wp-content/uploads/kalins-pdf/Post_Androgen_Deprivation_Syndrome.pdf