What type of pain do you get? is it tearing muscle pain? Is it while you’re on Pantoprazole?
It’s also CYP2C19 inhibitor, which is involved in fatty acid metabolism, testosterone and progesterone.
so I think you accumulate more progesterone because CYP2C19 has a higher affinity to it.
and progesterone is anti-androgen.
do you have blood tests?
are you male or female?
Dolore muscolare lacerante sia ai muscoli che tendini (gambe, anche, glutei e ginocchia) comparso circa 20 giorni la sospensione di finasteride. Sono maschio. Pantoprazolo sembra giovarmi almeno con riguardo alla perdita di peso e disbiosi intestinale. Il mio T alla data del 17.07.2024 circa 10 giorni dopo l’interruzione di Finasteride era a 291 ngdl
You have low T which is needed for muscles, ligaments, and joints, through its direct action and through its metabolites Estradiol and DHT.
you should stop taking Pantoprazole, even though it gives you symptomatic relief; it’s not good for you long-term.
You stopped Fin about 3 months ago, so you’re kind of new; let your body settle down and reach a plateau.
then do blood test, LH FSH T E prolactin DHT to check your levels.
ma ho paura che ci sia una mutazione del recettore AR e che il T mi faccia male per questo mi da sollievo il Pantoprazolo perchè quando non lo prendo dimagrisco ed aumentano i dolori. Sembra che sia diventato allergico al T il mio corpo evidentemente dopo 22 anni di fina non lo elabora più come dovrebbe e forse i recettori sono mutati e prima che si possano stabilizzare ci vorranno anni…
No you can’t mutate the receptors; it’s not possible; it is an epigenetic upregulation of the receptors
Your receptors are very sensitive to DHT; that’s why you get horrible symptoms from even low androgens and get relief from lowering androgens.
if you take progesterone, you will also feel relief.
but eventually you have to go through it so your body can downregulate AR to some extent and plateau.
You can try doing it gradually, like slowly tapering Pantoprazole if it helps.
Wow, 22 years of Fin that’s a lot, how could you stay on this poison for that long
Non me lo dire sono stato un idiota avevo smesso a gennaio ci sono ricascato a giugno per due settimane fino al 10 luglio ad agosto il danno totale con dolori allucinanti
Sei molto competente e preparato. Come stai tu? Che disturbi hai? Da quanto tempo?
If the estrogen receptors don’t function properly either, then I have little hope of improving and healing. I remember the story of poor Douglasmitch, which I read a long time ago, at the beginning of my illness. In the end, he committed suicide, as did others. I was saddened to read about young, healthy men taking their own lives because of a drug. It’s all very absurd. My symptoms are not static, they fluctuate based on my hormonal phases, and I’m keeping track of what helps me through a journal. I’ve been in this condition for almost three years. I hope I can endure!