Permanently low e2 after AI

General Discussion
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#1

Disclaimer: never took any 5ar inhibitor in my life.

Back in 2015 I used Pfizer Aromasin in the hope of boosting my natural testosterone. Which it worked really well for, I reached 1200ng/dl by just taking 25mg aromasin every 3 days.

I took it for about a month before the low e2 symptoms became unbearable:

  • crackly joints
  • flat muscles
  • no strength and 0 pump in the gym
  • depressed mood
  • foreharm hairloss
  • no libido.

Fast forward one year I didn’t learn from my mistake, I take aromasin again.
Same symptoms that make me stop.

Fast forward one year after discontinuing, I feel depressed, my muscles are flat, I cannot workout anymore, I have no libido.

I go for a blood test: e2 is <10, practically undetectable, and test is 600ng/dl.

Fast forward 3 years in 2020, another blood test: e2 still undetectable.

I decide to try transdermal testosterone to solve this issue: it does a great job at elevating e2, I feel a lot better, but it’s affecting my sleep really bad, and I don’t like that constant tiredness.

I’m now in a situation where I have found a solution to my low e2, but the solution makes me sleep-deprived.

Anyone has been confronted to the same issue and found a durable solution?

#2

What did your doctor say when you told them about the transdermal testosterone’s effect on you?

#3

Haven’t gone to a doctor and not sure I care about a doctor’s opinion on the matter, they are generally oblivious to this nature of issues.
Low T can be understood by few doctors.
Low e2 will be understood by almost none.

I’m self medicating with testosterone cream, I didn’t go to a doctor for it.

#4

And will you try estrogen cream? Do you think what dutasteride can do to 5ar, aromatase inhibitors can do the same to the aromatase enzyme and estrogen receptors?

#5

I won’t try estrogen cream.
I need to find a solution that increases endogenous aromatase.

#6

Taking a wild stab at fixing yourself with the advice of someone who may or may not know what they’re doing might not be the right thing to do.

Taking a wild guess, people posting on a forum looking for how to solve a problem, probably don’t have the answer themselves.

Whatever your current condition, we know that others who have experimented have in some cases dramatically worsened themselves.

1 Like
#7

Have you found a way to do this?